Performance of the FACT-GOG-Ntx to assess chemotherapy-induced peripheral neuropathy (CIPN) in pediatric high risk Hodgkin lymphoma: report from the Children’s Oncology Group AHOD 1331 study

Journal of Patient-Reported Outcomes

Table 5 Repeated measures model results for FACT-GOG-Ntx, n = 249

	β (SE)	p-value
Assessment time for youth
Time 1 (reference)
Time 2	− 0.77 (0.48)	0.11
Time 3	− 2.83 (0.48)	< 0.001
Assessment time for parent-proxy
Time 1 (reference)
Time 2	− 0.61 (0.44)	0.17
Time 3	− 1.99 (0.45)	< 0.001
Age (per year) for youth	− 0.03 (0.11)	0.80
Age (per year) for parent-proxy	− 0.27 (0.11)	0.01
Youth rater^a	− 0.33 (0.23)	0.15
Male sex	1.47 (0.35)	< 0.001

Restricted to youth and parent-proxy report of patients aged 11–17.9 years
Higher FACT-GOG-Ntx scores indicate less symptoms. Interaction between rater
and time had a p-value of 0.02. Interaction between rater and child age had a p-value
of 0.002.
^aEffect of youth rater is at Time 1 for a child of age 15 years