Psychometric evaluation of an electronic Asthma Symptom Diary for young children

Journal of Patient-Reported Outcomes

Table 10 Composite-level longitudinal construct validity correlations

ePASD score	ACQ-IA-5	ACQ-IA-6	C-ACT	PAQLQ(S) Overall	PAQLQ(S) Activity Limitation	PAQLQ(S) Symptoms	PAQLQ(S) Emotional Function	PGIS	CGIS	PGIC	CGIC
Change from Day 1 to EOS Day − 1 (n = 30–62)
Daytime Symptom score	−0.04	−0.02	−0.31	−0.09	0.05	−0.16	−0.07	0.06	−0.09	0.33	0.14
Daytime score	0.10	0.11	−0.27	−0.12	−0.00	−0.20	−0.04	0.08	−0.05	0.32	0.14
Nighttime Symptom score	0.10	0.09	−0.03	−0.16	−0.06	−0.19	−0.04	0.02	0.22	0.46*	0.32
Nighttime score	0.11	0.09	−0.03	−0.13	−0.05	−0.16	−0.03	−0.00	0.18	0.42*	0.30
Overall Symptom score	−0.08	−0.07	−0.21	−0.11	0.02	−0.16	−0.08	−0.01	−0.03	0.37*	0.17

* P < 0.01
ACQ-IA-5 = Asthma Control Questionnaire–Interviewer Administered, Symptoms Only; ACQ-IA-6 = Asthma Control Questionnaire–Interviewer Administered (including Item 6 Number of puffs); C-ACT = Childhood Asthma Control Test; CGIC = Caregiver Global Impression of Change; CGIS = Caregiver Global Impression of Severity; EOS = end of study; ePASD = electronic Pediatric Asthma Symptom Diary; PAQLQ(S) = Pediatric Asthma Quality of Life Questionnaire–Standardized; PGIC = Patient Global Impression of Change; PGIS = Patient Global Impression of Severity
Notes: ePASD change was computed using study Day 1 and EOS Day − 1 data; Day 1 and EOS data were used to compute change for the PAQLQ(S), CACT, ACQ-IA-5, ACQ-IA-6, PGIS, CGIS, PGIC, and CGIC. Correlation coefficients in bold were hypothesized to be relatively strong