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Table 4 Convergent and discriminant analyses: Correlation between PROMIS Fatigue SF-7a scores and IBDQ items at Week 12

From: Qualitative and psychometric evaluation of the PROMIS®-Fatigue SF-7a scale to assess fatigue in patients with moderately to severely active inflammatory bowel disease

IBDQ questions/items

CD patients

UC patients

(N = 305)

(N = 204)

Accidental soiling of underpants

-0.44

-0.50

Angry because of bowel problem

-0.54

-0.62

Avoid events where no washroom

-0.57

-0.61

Delay or cancel social engagement

-0.57

-0.60

Difficulty leisure/sports activity

-0.68

-0.62

Embarrassed by bowel problem

-0.59

-0.63

Energy

-0.77

-0.60

Fear of not finding a washroom

-0.54

-0.54

Feeling of fatigue or tiredness

-0.80

-0.70

Felt depressed or discouraged

-0.61

-0.68

Felt generally unwell

-0.65

-0.66

Felt irritable

-0.59

-0.63

Felt relaxed and free of tension

-0.61

-0.59

Felt tearful or upset

-0.52

-0.62

Frustrated, impatient, restless

-0.66

-0.66

Going to bathroom, empty bowels

-0.52

-0.54

Lack of understanding from others

-0.49

-0.62

Limited sexual activity

-0.50

-0.56

Loose bowel movements

-0.44

-0.50

Nausea, feeling sick to stomach

-0.48

-0.57

Problem large amounts of gas

-0.42

-0.53

Problem maintaining/losing weight

-0.51

-0.46

Problems with sleep

-0.62

-0.52

Rectal bleeding

-0.26

-0.40

Satisfied, happy with personal life

-0.53

-0.56

Troubled by abdominal bloating

-0.51

-0.52

Troubled by cramps in abdomen

-0.55

-0.56

Troubled by pain in the abdomen

-0.53

-0.50

Unable to attend school/do work

-0.57

-0.54

Worried or anxious

-0.55

-0.56

Worried, possibility of surgery

-0.45

-0.41

  1. CD, Crohn’s disease; IBDQ, Inflammatory Bowel Disease Questionnaire; PROMIS, Patient-reported Outcomes Measurement Information System; SF-7a, Short Form-7a; UC, ulcerative colitis. Strong correlations (rs ≥ -0.70) between fatigue-related IBDQ items and mean SF-7a scores are bolded