Total (n = 45) | Not severe MR (n = 33) | Severe MR (n = 12) | p value | |
---|---|---|---|---|
LVAD pump parameters† | ||||
Speed (rpm) | 5.263 ± 222 | 5.292 ± 245 | 5.183 ± 111 | 0.15 |
Flow (L/min) | 4.4 ± 0.4 | 4.4 ± 0.5 | 4.4 ± 0.4 | 0.96 |
Power (W) | 3.8 ± 0.4 | 3.8 ± 0.3 | 3.9 ± 0.4 | 0.41 |
Pulsatile index | 3.6 ± 0.8 | 3.7 ± 0.9 | 3.6 ± 0.6 | 0.72 |
ECMO | 6 (13.3%) | 3 (9.1%) | 3 (25.0%) | 0.37 |
RVAD | 4 (8.9%) | 2 (6.1%) | 2 (16.7%) | 0.61 |
Visual assessment RVF‡ | 0.26 | |||
Normal | 2 (4.4%) | 2 (6.1%) | 0 (0%) | |
Mildly reduced | 20 (44.4%) | 17 (51.5%) | 3 (25.0%) | |
Moderately reduced | 16 (33.6%) | 10 (30.3%) | 6 (50.0%) | |
Severely reduced | 7 (15.6%) | 4 (12.1%) | 3 (25.0%) | |
Suction events | 14 (31.1%) | 11 (33.3%) | 3 (25.0%) | 0.87 |
Pump thrombosis | 2 (4.4%) | 1 (3.0%) | 1 (8.3%) | 1 |
VT detected overall | 15 (33.3%) | 10 (30.3%) | 5 (41.7%) | 0.72 |
VT requiring hospital visit | 5 (11.1%) | 4 (12.1%) | 1 (8.3%) | 1 |
Ischemic stroke | 4 (8.9%) | 3 (9.1%) | 1 (8.3%) | 1 |
Bleeding events | ||||
Cerebral bleeding | 2 (4.4%) | 1 (3.0%) | 1 (8.3%) | 1 |
GIB | 3 (6.7%) | 2 (6.1%) | 1 (8.3%) | 1 |
Epistaxis | 5 (11.1%) | 5 (15.2%) | 0 (0%) | 0.37 |
Re-thoracotomy | 2 (4.4%) | 2 (6.1%) | 0 (0%) | 0.96 |
NYHA Class ≥ III | ||||
Post-LVAD† | 16/39 (41.0%) | 13/29 (44.8%) | 3/10 (30.0%) | 0.65 |
Time point of health status | 11/40 (27.5%) | 9/30 (30.0%) | 2/10 (20.0%) ara> | 0.70 |
6 MWT [m] | ||||
Post-LVAD† | 380.5 ± 127.1 | 372.4 ± 133.1 | 401.4 ± 113.3 | 0.53 |
Time point of health status | 431.4 ± 98.1 | 431.2 ± 95.9 | 431.8 ± 107.2 | 0.99 |