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Journal of Patient-Reported Outcomes

Table 3 Important difference of FACIT-Fatigue by EORTC Global Health Status/QoL score and EORTC Fatigue scale

From: Clinically important change for the FACIT-Fatigue scale in paroxysmal nocturnal hemoglobinuria: a derivation from international PNH registry patient data

 

EORTC Global Health Status/QoL scorec

Q1 (n = 90)

Q2 (n = 98)

Q3 (n = 111)

Q4 (n = 120)

Difference (range)

Mean FACIT-Fatigue Scorea

15.7

25.5

31.1

40.9

8.4 (5.6–9.8)

P valueb

    

 < 0.0001

 

EORTC Fatigue scale scored

Q1 (n = 84)

Q2 (n = 117)

Q3 (n = 96)

Q4 (n = 121)

Difference (range)

Mean FACIT-Fatigue Scorea

44.8

36.0

24.4

16.3

− 9.5 (− 8.1 to − 11.6)

P valueb

    

 < 0.0001

  1. EORTC European Organization for the Research and Treatment of Cancer, FACIT functional assessment of chronic illness therapy, QoL quality of life
  2. aHigher FACIT-Fatigue scores indicate less fatigue
  3. bP value is calculated using the analysis of variance (ANOVA)
  4. cIncreasing quartiles for EORTC Global Health Status/QoL indicate higher functioning
  5. dIncreasing quartiles for EORTC Fatigue Scale indicate more fatigue
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