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Journal of Patient-Reported Outcomes
Fig. 3 | Journal of Patient-Reported Outcomes

Fig. 3

From: Clinically important change for the FACIT-Fatigue scale in paroxysmal nocturnal hemoglobinuria: a derivation from international PNH registry patient data

Fig. 3

Change in percentage of patients with HDA at baseline and no HDA during follow-up by FACIT-Fatigue score change. CIC, clinically important change; FACIT, Functional Assessment of Chronic Illness Therapy; HDA, high disease activity (defined as lactate dehydrogenase ≥ 1.5 × upper limit of normal and ≥ 1 PNH symptom); PNH, paroxysmal nocturnal hemoglobinuria. *CIC reflects the SEM-derived value of 5 points

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