Adaptation and validation of the Hungarian version of Thyroid-Related Patient-Reported Outcome-39 (ThyPro-39) questionnaire: testing factor structure, known-group validity with the comparison of quality of life in Hashimoto’s thyroiditis and Graves’ disease

Journal of Patient-Reported Outcomes

Table 7 CFA with covariates model

	Age	Sex	Diagnosis	Perceived Stress	R ²
Psychosocial symptoms factor	0.12*	0.10*	0.11*	0.80***	63.8%
Somatic symptoms factor	0.20**	-0.01	-0.15*	0.34***	14.5%
Tiredness	-0.20	-0.07	-0.20	-0.35	18.2%
Cognitive problems	-0.27***	-0.09	-0.27***	-0.34*	24.0%
Anxiety	-0.25***	-0.02	-0.11	0.43***	30.3%
Depressivity	-0.07	0.02	-0.07	0.37**	15.7%
Emotional suspectibility	-0.12*	-0.02	-0.08	0.38***	18.3%
Impaired social life	-0.13	-0.04	-0.12	0.01	3.4%
Imapired daily life	-0.01	-0.13	-0.24*	-0.32	17.4%
Goitre symptoms	-0.10	-0.01	-0.03	-0.07	1.3%
Hyperthyroid symptoms	-0.01	0.06	0.32**	0.17	12.8%
Hypothyroid symptoms	0.19*	0.20*	-0.01	-0.02	9.4%
Eye symptoms	0.30***	0.01	0.34***	0.03	20.7%
Cosmetic complaints	-0.09	0.11	0.31**	0.09	11.3%

Note: N = 286. Standardized regression coefficients. Sex is coded: 1 = Male; 2 = Female. Diagnosis is coded: 1 = Hashimoto; 2 = Graves). *:p < .05; **:p < .01; ***:p < .001. To keep Type I error under control, we regard coefficients significant if p < .01, these coefficients are in bold