Table 3 Regression models predicting HRQOL and proposed mediators

Adverse Experiences

− 0.19

 < .001

− 0.02

.527

0.15

 < .001

0.21

 < .001

0.29

 < .001

0.25

 < .001

0.33

 < .001

Age

0.15

 < .001

− 0.07

.029

− 0.19

 < .001

− 0.31

 < .001

− 0.15

 < .001

− 0.17

 < .001

− 0.27

 < .001

Female gender

0.03

.446

0.08

. 005

0.09

.013

0.14

 < .001

0.10

.004

0.07

.099

− 0.05

.135

Diverse race or ethnicity

− 0.06

.067

− 0.05

.060

0.01

.645

− 0.01

.701

0.06

. 104

0.03

.543

0.07

.053

Years since dx

0.07

.047

0.07

.009

0.07

.039

0.02

. 482

0.03

.382

0.04

.395

0.00

.946

Vaccinated for covid

0.01

.657

0.10

 < .001

0.14

 < .001

0.14

 < .001

0.07

.044

0.18

 < .001

0.01

.960

Days since vaccine available

− 0.05

.158

− 0.06

.038

0.01

.731

− 0.03

.433

− 0.02

.497

− 0.07

.105

0.02

.652

Perceived benefits

− 0.01

.899

0.04

.383

Social support

0.04

.567

0.11

.145

Stress management

0.39

 < .001

0.18

.008

AdvrsExp*benefit

− 0.01

.774

0.00

.939

AdvrsExp*soc_supp

− 0.07

.292

− 0.06

. 391

AdvrsExp*StressManage

0.09

.152

0.05

.439

Covid anxiety

0.03

.614

Covid depression

− 0.49

 < .001

Health disruptions

0.03

.489

Daily disruptions

− 0.16

.070

Financial burden

−0.13

.003

Total

− 0.19

 < .001

[− 0.25, −0.12]

Indirect, COVID anxiety

0.00

.629

[− 0.01, 0.02]

Indirect, COVID depression

− 0.10

 < .001

[−0.15, −0.07]

Indirect, health disruptions

0.01

.493

[− 0.02, 0.04]

Indirect, daily disruptions

− 0.04

.094

[− 0.09, 0.00]

Indirect, financial burden

− 0.04

.004

[− 0.07, − 0.01]