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Table 1 Respiratory symptoms inter-Item (Polychoric) correlations in participants with RSV-positive disease status

From: Evaluation of symptoms in respiratory syncytial virus infection in adults: psychometric evaluation of the Respiratory Infection Intensity and Impact Questionnaire™ symptom scores

RiiQ™ respiratory item

Polychoric correlation

a. Cough

b. Sore throat

d. Nasal congestion

j. Wheezing

k. Expectoration

Vaccine trial—ARI PRO eDiary Day 1 (n = 40)

 a. Cough

    

 b. Sore throat

0.37

(0.04, 0.69)

   

 d. Nasal congestion

− 0.03

(− 0.40, 0.33)

− 0.16

(− 0.53, 0.20)

  

 j. Wheezing

0.53

(0.22, 0.84)

0.27

(− 0.11, 0.65)

− 0.10

(− 0.51, 0.31)

 

 k. Expectoration

0.58

(0.32, 0.84)

0.19

(− 0.17, 0.54)

0.02

(− 0.35, 0.40)

0.55

(0.26, 0.85)

 l. Shortness of breath

0.69

(0.44, 0.94)

0.29

(− 0.09, 0.68)

0.27

(− 0.12, 0.67)

0.53

(0.19, 0.87)

0.84

(0.69, 1.00)

HARTI—baseline (n = 100)

 a. Cough

    

 b. Sore throat

0.53

(0.31, 0.74)

   

 d. Nasal congestion

0.33

(0.13, 0.54)

0.35

(0.10, 0.60)

  

 j. Wheezing

0.62

(0.47, 0.78)

0.39

(0.15, 0.63)

0.47

(0.29, 0.66)

 

 k. Expectoration

0.36

(0.16, 0.56)

0.23

(− 0.03, 0.49)

0.24

(0.03, 0.46)

0.37

(0.17, 0.57)

 l. Shortness of breath

0.65

(0.51, 0.80)

0.51

(0.29, 0.72)

0.40

(0.20, 0.60)

0.76

(0.65, 0.87)

0.21

(− 0.01, 0.43)

  1. Bolded cells indicate a lower respiratory tract symptom
  2. ARI acute respiratory infection, PRO patient-reported outcome, RiiQ™ Respiratory Infection Intensity and Impact Questionnaire, RSV respiratory syncytial virus
  3. Items truncated. Complete items available from the author