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Table 4 Test-retest reliability of AE-QoL total and domain scores at Week 9 and Week 13

From: Content validation and psychometric evaluation of the Angioedema Quality of Life Questionnaire for hereditary angioedema

AE-QoL score (n = 42)

Week 9

mean (SD)

Week 13

mean (SD)

Mean change (SD)

t-test statistic,

p value

ICC (95% CI)

Total score

33.37 (23.33)

33.02 (21.83)

−0.35 (14.37)

−0.16, 0.8753

0.89 (0.80–0.94)

Functioning

25.00 (25.94)

26.34 (28.84)

1.34 (21.23)

0.41, 0.6848

0.83 (0.68–0.91)

Fatigue/Mood

32.74 (23.01)

30.00 (21.21)

−2.74 (17.71)

−1.00, 0.3222

0.81 (0.65–0.90)

Fears/Shame

39.68 (29.78)

41.07 (28.66)

1.39 (19.25)

0.47, 0.6426

0.88 (0.78–0.94)

Food

32.74 (31.59)

29.76 (32.78)

−2.98 (20.99)

−0.92, 0.3635

0.88 (0.78–0.94)

  1. AE-QoL Angioedema Quality of Life Questionnaire; ICC intraclass coefficient