Table 5 Number of responsiveness hypotheses confirmed
|  | Correlation ≥ 0.40 with similar domains | Highest correlation with similar SF-12 domains | Highest correlation with similar DSI domains | Higher correlation with DSI total number of symptoms and changes in symptom severity than with other DSI scores | At least similar or slightly higher effect sizes for PROMIS CAT compared to comparable SF-12 domains | At least similar or slightly higher effect sizes for PROMIS CAT compared to comparable DSI items | AUC ≥ 0.70 | Total number of hypotheses confirmed (%) |
|---|---|---|---|---|---|---|---|---|
PROMIS CAT | Â | Â | Â | Â | Â | Â | Â | Â |
Physical Function | 2/2 | 3/3 | NA | 1/2 | 3/3 | NA | 1/1 | 10/11(91) |
Pain Interference | 2/3 | 2/2* | NA | 2/2 | 1/2* | NA | 0/1 | 7/10 (70) |
Fatigue | 2/3 | 1/1 | 1/1 | 2/2 | 0/1 | 1/1 | 1/1 | 8/10 (80) |
Sleep Disturbance | 1/2 | NA | 1/1 | 2/2 | NA | 1/1 | 1/1 | 6/7 (86) |
Anxiety | 1/4 | 3/3 | 1/1 | 2/2 | 1/3 | 1/1 | 0/1 | 9/15 (60) |
Depression | 2/3 | 3/3 | NA | 2/2 | 1/3 | NA | 1/1 | 9/12 (75) |
Ability to Participate in Social Roles and Activities | 1/4 | 0/3 | NA | 2/2 | 2/2 | NA | 0/1 | 5/12 (42) |