Responsiveness and minimal important change of seven PROMIS computerized adaptive tests (CAT) in patients with advanced chronic kidney disease

Journal of Patient-Reported Outcomes

Table 2 Characteristics of the study population at baseline (n = 207)

	n (%) or mean (SD)
Sex, male	124 (59.9)
Age, years	65.5 (13.8)
Ethno-cultural group^$, Dutch	176 (85.0)
Educational level^#
Low	85 (41.0)
Middle	49 (23.7)
High	73 (35.3)
Primary kidney disease
Glomerulonephritis	34 (16.6)
Pyelonephritis	7 (3.4)
Polycystic kidney disease	16 (7.8)
Other congenital/hereditary kidney diseases	15 (7.3)
Hypertension/renal vascular disease	46 (22.5)
Diabetes mellitus	14 (6.8)
Miscellaneous	63 (30.7)
Unknown	10 (4.9)
Kidney function, eGFR (ml/min.1.73 m²)	21.4 (6.7)
KRT in medical history^£, yes	35 (17.0)
BMI, kg/m²	26.8 (5.2)
Smoking
Yes	25 (13.2)
No, stopped	94 (49.7)
No, never smoked	70 (37.0)
Comorbidities
Hypertension, yes	164 (79.2)
Diabetes mellitus, yes	62 (30.0)
Cardiovascular disease, yes	53 (25.6)
Lung disease, yes	30 (14.5)
Liver disease, yes	11 ( 5.3)
Malignancy, yes	50 (24.2)

^$ Self-reported ethno-cultural group: “What ethnic group do you consider yourself to belong to?“
^# Educational level according to International Standard Classification of Education (ISCED) levels 2011, classified as low: primary, lower secondary or lower vocational education; middle: upper secondary or upper vocational education; high: tertiary education (college/university)
^£ KRT in medical history includes patients who have undergone (temporary) dialysis treatment or had received a kidney transplant in the past. At study inclusion, all patients had an eGFR < 30 and did not require dialysis treatment, in accordance with inclusion criteria
Missing values for population at baseline: primary kidney disease: n = 2 (1.0%); KRT in medical history: n = 1 (0.5%); BMI: n = 11 (5.3%); smoking: n = 18 (8.7%)
Abbreviations: BMI = body mass index; eGFR = estimated glomerular filtration rate; KRT = kidney replacement therapy