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Table 6 Construct validity correlations of ASD total scores

From: Development and evaluation of the Acromegaly Symptom Diary

ASD score

Correlations with supporting measures

 

PGI-S

EQ-VAS

AcroQoL Total

Baseline (n = 19 to 31)

   

Total score

0.65*

− 0.53*

− 0.61*

Item 1. Headache pain

0.38*

− 0.41*

− 0.44*

Item 2. Joint pain

0.58*

− 0.60*

− 0.52*

Item 3. Sweating

0.52*

− 0.36*

− 0.40*

Item 4. Fatigue

0.62*

− 0.40*

− 0.57*

Item 5. Leg weakness

0.53*

− 0.42*

− 0.52*

Item 6. Swelling

0.59*

− 0.41*

− 0.54*

Item 7. Numbness/tingling

0.43*

− 0.42*

− 0.47*

Item 8. Sleep difficulty

0.42*

− 0.37*

− 0.40*

Item 9. Short-term memory

0.56*

− 0.51*

− 0.53*

Week 17 (n = 16 to 27)

   

Total Score

0.67*

− 0.47*

− 0.66*

Item 1. Headache pain

0.54*

− 0.27

− 0.43*

Item 2. Joint pain

0.50*

− 0.35

− 0.45*

Item 3. Sweating

0.19

− 0.15

− 0.25

Item 4. Fatigue

0.49*

− 0.37

− 0.58*

Item 5. Leg weakness

0.43*

− 0.53*

− 0.47*

Item 6. Swelling

0.68*

− 0.30

− 0.44*

Item 7. Numbness/‌tingling

0.37

− 0.17

− 0.46*

Item 8. Sleep difficulty

0.27

− 0.36

− 0.38

Item 9. Short-term memory

0.25

− 0.31

− 0.31

  1. *P < 0.05 test for H0: ρ = 0
  2. AcroQoL = Acromegaly Quality of Life Questionnaire; ASD = Acromegaly Symptoms Diary; EQ-VAS = EQ visual analogue scale; PGI-S = Patient Global Impression of Severity
  3. Bold values indicate correlation values were hypothesized to be moderate to strong