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Journal of Patient-Reported Outcomes

Table 5 AcroQoL and PASQ scores in relation to acromegaly complications

From: Associations between paraclinical parameters, symptoms and quality of life in patients with acromegaly: a cross sectional study

Cardiovascular complications

Yes, n = 20

No, n = 11

p value

AcroQoL

Physical

51.25 (± 23.08)

64.77 (± 18.23)

0.1051

Psychological

56.96 (± 21.78)

73.21 (± 16.01)

0.0386*

Appearance

52.86 (± 21.48)

63.96 (± 23.88)

0.1957

Interpersonal relations

61.07 (± 24.88)

82.47 (± 12.92)

0.0129*

Total score

54.89 (± 20.61)

70.14 (± 16.04)

0.0425*

PASQ

Headaches

2.66 (± 2.30)

1.90 (± 2.11)

0.3837

Excessive sweating

3.55 (± 2.79)

2.72 (± 2.28)

0.4151

Joint pain

3.77 (± 2.73)

2.81 (± 2.44)

0.3488

Fatigue

3.83 (± 2.43)

2.90 (± 2.02)

0.3007

Soft tissue swelling

2.61 (± 2.52)

1.81 (± 1.94)

0.3807

Overall

16.44 (± 2.23)

12.18 (± 6.60)

0.2033

Type 2 Diabetes mellitus

Yes, n = 12

No, n = 19

p value

AcroQoL

Physical

47.14 (± 19.87)

61.68 (± 22.17)

0.0746

Psychological

54.02 (± 14.19)

68.23 (± 23.27)

0.0677

Appearance

44.64 (± 13.83)

64.47 (± 23.97)

0.0147*

Interpersonal relations

63.39 (± 18.60)

71.99 (± 26.17)

0.3309

Total score

51.52 (± 13.17)

65.85 (± 22.09)

0.0531

PASQ

Headaches

3.18 (± 2.48)

1.88 (± 1.96)

0.0042*

Excessive sweating

4.63 (± 2.76)

2.38 (± 2.14)

0.0209*

Joint pain

4.18 (± 2.44)

2.94 (± 2.68)

0.2244

Fatigue

3.91 (± 1.64)

3.22 (± 2.62)

0.4439

Soft tissue swelling

3.18 (± 2.71)

1.77 (± 1.92)

0.1147

Overall

19.09 (± 8.17)

12.22 (± 8.05)

0.0354*

Pituitary insufficiency

Yes, n = 20

No, n = 11

p value

AcroQoL

Physical

59.09 (± 14.62)

54.38 (± 25.60)

0.5797

Psychological

58.12 (± 17.83)

65.27 (± 22.84)

0.3772

Appearance

51.62 (± 19.32)

59.64 (± 24.23)

0.3535

Interpersonal relations

64.61 (± 22.22)

70.89 (± 24.56)

0.4871

Total score

58.47 (± 14.64)

61.31 (± 23.05)

0.7157

PASQ

Headaches

2.33 (± 1.93)

2.36 (± 2.45)

0.9703

Excessive sweating

4.00 (± 2.34)

2.68 (± 2.58)

0.2069

Joint pain

2.44 (± 2.29)

3.78 (± 2.70)

0.2169

Fatigue

2.88 (± 1.36)

3.57 (± 2.54)

0.4551

Soft tissue swelling

2.22 (± 2.81)

2.31 (± 2.18)

0.9240

Overall

13.89 (± 7.40)

14.74 (± 9.26)

0.8122

  1. p values < 0.05 were marked as bold, revealing statistical significant differences
  2. Mean AcroQoL and PASQ scores for each scale in relation to the presence of acromegaly-specific complications. Standard deviations are expressed in parentheses. *Mann–Whitney test was applied to compare the groups (with and without complications), a p value < 0.05 was considered statistically significant
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