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Table 3 Concept-to-item mapping

From: Development and content validation of the Symptoms Evolution of COVID-19: a patient-reported electronic daily diary in clinical and real-world studies

Theme Symptom SE-C19 Item
Upper respiratory tract Head congestion   
Stuffy/congested nose   
Runny nose Runny nose
Postnasal drip   
Phlegm Sputum/phlegm
Sneezing Sneezing
Sore throat lost voice Sore throat
Sinus pressure/pain   
Swollen glands   
Earache   
Lower respiratory tract Cough Cough
Chest pressure/tightness Pressure/tightness in chest
Chest pain Chest pain
Shortness of breath Shortness of breath/difficulty breathing
Difficulty breathing Shortness of breath/difficulty breathing
Systemic Fever Feverish
Chills Chills
Sweating   
Body ache Body aches such as muscle pain or joint pain
Muscle ache Body aches such as muscle pain or joint pain
Joint pain Body aches such as muscle pain or joint pain
Headache/migraine Headache
Back pain Body aches such as muscle pain or joint pain
Physical fatigue/sleepiness Fatigue
Mental fatigue Confusion
Do not feel like self   
Weakness   
Dizzy/lightheaded Dizziness
Heart palpitations   
Loss of appetite Loss of appetite
Gastrointestinal Nausea Nausea
Vomiting Vomiting
Diarrhea Diarrhea
Constipation   
Stomachache Stomachache
Smell and taste Altered taste   
Altered smell   
Loss of taste Loss of taste/smell
Loss of smell Loss of taste/smell
Other Skin rash Rash
Skin redness   
Red eyes Red or watery eyes
Watery eyes Red or watery eyes
Numb feet   
  1. SE-C19 Symptoms Evolution of COVID-19. indicates direct mapping to SE-C19 question. ≈ indicates indirect mapping to SE-C19 question