Table 8 Unadjusted mean scores (± SD) of EORTC QLQ-NMIBC24 subscales for 541 NMIBC patients participating in UroLife at three time points after diagnosis and mean differences at 3 months (T3mo) and 15 months (T15mo) compared to 6 weeks (T6wk) after diagnosis (responsiveness)
Patient score, mean (SD) | Effect sizea | ||||
|---|---|---|---|---|---|
T6wk (N = 541) | T3mo (N = 471) | T15mo (N = 423) | T3mo vs. T6wk | T15mo vs. T6wk | |
Urinary symptoms (–)e | 28.4 (21.0) | 22.3 (19.3) | 17.8 (16.4) | − 0.27d | − 0.53d |
Malaise (–)e | 3.7 (12.1) | 3.4 (10.5) | 2.5 (9.5) | − 0.02 | − 0.08 |
Future worries (–)e | 33.6 (24.1) | 29.5 (22.6) | 24.7 (21.4) | − 0.17d | − 0.38d |
Bloating and flatulence (–)e | 17.4 (21.2) | 17.1 (20.4) | 14.4 (18.0) | 0.00 | − 0.14c |
Sexual functioning (+)e | 21.9 (22.6) | 24.4 (22.2) | 27.1 (23.2) | 0.09d | 0.23d |
Male sexual problems (–)e | 28.1 (32.6) | 27.5 (31.2) | 33.3 (33.0) | − 0.01 | 0.12b |
Intravesical treatment issues (–)e | 10.0 (18.8) | 9.5 (18.7) | 6.2 (15.7) | 0.02 | − 0.23d |
Sexual intimacy (–)e | 13.8 (22.4) | 10.4 (20.0) | 10.1 (19.2) | − 0.20c | − 0.29c |
Risk of contaminating partner (–)e | 19.3 (27.0) | 14.3 (22.7) | 10.0 (21.5) | − 0.20b | − 0.46d |
Sexual enjoyment (+)e | 45.0 (29.7) | 42.9 (26.5) | 41.9 (29.1) | − 0.12 | − 0.20b |
Female sexual problems (–)e | 33.3 (25.8) | 18.8 (36.5) | 12.7 (24.7) | − 0.34 | − 1.16b |