Table 3 Health-related quality of life (HRQOL) scores by mode of administration
Domain questionnaire and scale | PSAQ mean (SD) | CSAQ mean (SD) | IVR mean (SD) |
|---|---|---|---|
Global/general health | |||
PROMIS global mental | 48.6 (8.2) | 49.6 (8.5) | 50.4 (7.9) |
PROMIS global physical | 43.7 (8.3) | 44.0 (8.5) | 44.1 (7.6) |
NRS overall QOL | 72.6 (20.7) | 74.4 (20.2) | 72.2 (21.5) |
NRS emotional well-being | 75.7 (21.0) | 77.1 (19.4) | 75.3 (20.4) |
NRS mental well-being | 80.2 (19.6) | 81.1 (18.4) | 78.8 (19.7) |
Physical function | |||
PROMIS physical function | 43.7 (8.3) | 44.0 (8.5) | 44.1 (7.6) |
NRS physical well-being | 69.6 (22.4) | 71.2 (20.2) | 71.9 (21.6) |
Social function | |||
PROMIS social function | 48.5 (9.6) | 49.0 (9.6) | 49.2 (8.8) |
NRS social activity | 66.0 (26.0) | 68.5 (24.1) | 69.6 (23.9) |
Emotional distress—anxiety | |||
PROMIS anxiety | 50.2 (9.8) | 49.3 (9.6) | 49.2 (9.2) |
NRS anxiety | 28.2 (26.6) | 27.6 (27.3) | 22.7 (24.1) |
PRO-CTCAE anxiety frequency | 32.2 (25.9) | 29.3 (25.1) | 25.0 (24.6) |
PRO-CTCAE anxiety severity | 27.7 (24.1) | 25.0 (23.1) | 22.0 (22.2) |
PRO-CTCAE anxiety interference | 16.9 (23.2) | 15.3 (22.9) | 12.2 (19.8) |
Emotional distress—depression | |||
PROMIS depression | 48.0 (9.1) | 47.4 (8.9) | 48.1 (7.8) |
NRS depression | 17.4 (23.1) | 16.7 (23.2) | 12.7 (18.7) |
PRO-CTCAE cheer frequency | 16.4 (22.5) | 15.7 (22.8) | 12.7 (19.5) |
PRO-CTCAE cheer severity | 14.3 (22.0) | 13.0 (20.8) | 10.4 (17.4) |
PRO-CTCAE cheer interference | 12.4 (20.9) | 10.7 (20.1) | 9.0 (17.1) |
PRO-CTCAE sad frequency | 29.4 (23.8) | 27.7 (24.0) | 24.3 (20.4) |
PRO-CTCAE sad severity | 24.1 (21.7) | 23.3 (22.2) | 20.0 (19.7) |
PRO-CTCAE sad interference | 14.8 (21.8) | 13.6 (21.7) | 11.4 (18.6) |
Fatigue | |||
PROMIS fatigue | 53.0 (9.0) | 52.2 (9.4) | 51.0 (8.7) |
NRS fatigue | 40.7 (26.0) | 39.5 (27.1) | 33.9 (24.6) |
PRO-CTCAE fatigue severity | 41.2 (23.8) | 39.8 (24.5) | 36.5 (23.4) |
PRO-CTCAE fatigue interference | 36.7 (26.8) | 36.3 (27.7) | 31.8 (24.8) |
Sleep | |||
PROMIS sleep disturbance | 50.1 (9.6) | 49.2 (9.3) | 49.6 (8.9) |
NRS sleep overall | 36.5 (25.2) | 33.7 (23.5) | 34.4 (23.4) |
PRO-CTCAE sleep severity | 33.9 (26.9) | 30.2 (25.8) | 28.1 (25.9) |
PRO-CTCAE sleep interference | 25.5 (26.1) | 25.1 (26.3) | 21.1 (24.1) |
Pain | |||
PROMIS pain intensity | 49.7 (10.6) | 49.5 (11.0) | 48.4 (10.8) |
PROMIS pain interference | 51.8 (9.9) | 51.3 (10.0) | 50.7 (9.5) |
NRS pain frequency | 29.3 (29.4) | 27.8 (28.7) | 26.0 (28.7) |
NRS pain severity | 25.9 (26.2) | 25.9 (27.1) | 23.7 (25.5) |
PRO-CTCAE pain frequency | 38.0 (30.6) | 38.6 (32.0) | 35.1 (31.8) |
PRO-CTCAE pain severity | 32.0 (26.8) | 32.1 (27.9) | 30.2 (28.4) |
PRO-CTCAE pain interference | 24.5 (27.9) | 24.7 (28.7) | 22.1 (26.8) |