Measuring respiratory symptoms in moderate/severe asthma: evaluation of a respiratory symptom tool, the E-RS®: COPD in asthma populations

Journal of Patient-Reported Outcomes

Table 2 Item concepts mapped to E-RS: COPD and supplemental items in the qualitative study

E-RS: COPD items	Item concept reported in literature	Item concept reported by clinicians (N = 2)	Item concept reported during patient interviews
E-RS: COPD items	Item concept reported in literature	Item concept reported by clinicians (N = 2)	Spontaneous	Probed	Total, n (%) (N = 25)
Item 1: Chest congestion^a	✓	✓	4	14	18 (72)
Item 2: Cough	✓	✓	8	12	20 (80)
Item 3: Mucus/phlegm^a	✓	✓	4	14	18 (72)
Item 4: Difficulty bringing up mucus/phlegm^a	✓	✓	4	14	18 (72)
Item 5: Chest discomfort	NR	NR	0	5	5 (20)
Item 6: Chest tightness	✓	✓	7	15	22 (88)
Item 7: Breathlessness	✓	✓	13	9	22 (88)
Item 8: Description of breathlessness	✓	✓	13	9	22 (88)
Item 9: Short of breath with personal care activities^b	✓	✓	1	13	14 (56)
Item 10: Short of breath with indoor activities	✓	✓	17	8	25 (100)
Item 11: Short of breath with outdoor activities^c	✓	✓	6	19	25 (100)

^aPatients described various aspects of sputum/mucus production; ^bpatients described shortness of breath at rest or with minimal physical activity; ^cpatients described shortness of breath with exertion. ✓, reported; E-RS: COPD, Evaluating Respiratory Symptoms in Chronic Obstructive Pulmonary Disease; NR, not reported