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Table 4 Impacts of hATTR Amyloidosis on patients’ functioning and well-being

From: Patient-reported burden of hereditary transthyretin amyloidosis on functioning and well-being

Impacta N (%)
Physical Functioning
 Difficulty gripping/holding 11 (79%)
 Difficulty walking/standing 11 (79%)
 Difficulty bending/kneeling 5 (36%)
 Difficulty climbing stairs/ladders 5 (36%)
 Difficulty lifting heavy items 4 (29%)
 Difficulty exercising 4 (29%)
 Idleness 4 (29%)
Emotional Well-being
 Fear/anxiety 10 (71%)
 Frustration/disappointment 7 (50%)
 Sadness/depression 6 (43%)
 Anguish/despair 4 (29%)
Social Functioning
 Unable to participate in social activities 11 (79%)
 Misunderstood by others 4 (29%)
 Difficulty communicating 2 (12%)
 Self-isolation 2 (12%)
Work and Activities of Daily Living
 Early retirement 8 (57%)
 Absenteeism 8 (57%)
 Presenteeism 7 (50%)
 Difficulty dressing, bathing, using bathroom 9 (64%)
 Difficulty performing household chores 8 (57%)
 Difficulty driving 8 (57%)
 Difficulty eating 3 (21%)
  1. aBecause patients could report multiple impacts, frequency sums to > 100%