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Table 3 Significance Testing for Difference in Preference between Devices on Each Item of the DID-PQ (N = 310)

From: Validity and analysis of the Diabetes Injection Device Preference Questionnaire (DID-PQ)

DID-PQ Items

Na

Prefer Dulaglutide Deviceb

n (%)

Prefer Semaglutide Devicec

n (%)

p-valued

1. Ease of preparing the injection device and medication for use

302

280 (92.7%)

22 (7.3%)

<.0001

2. Ease of fitting the injection into your routine

260

235 (90.4%)

25 (9.6%)

<.0001

3. Ease of bringing the injection device with you when it is necessary to inject away from home

260

219 (84.2%)

41 (15.8%)

<.0001

4. Confidence that the injection device provides the correct dose of medication every time

270

234 (86.7%)

36 (13.3%)

<.0001

5. Confidence that you are using the injection device correctly

269

245 (91.1%)

24 (8.9%)

<.0001

6. The size of the needle

188

159 (84.6%)

29 (15.4%)

<.0001

7. The time it takes to prepare and inject each dose of medication

285

270 (94.7%)

15 (5.3%)

<.0001

8. Overall satisfaction with the injection device

285

255 (89.5%)

30 (10.5%)

<.0001

9. Overall ease of using the injection device (gated secondary outcome)

290

269 (92.8%)

21 (7.2%)

<.0001

10. Overall convenience of using the injection device

293

267 (91.1%)

26 (8.9%)

<.0001

  1. Abbreviations: DID-PQ Diabetes Injection Device Preference Questionnaire
  2. a Excludes all neutral and missing responses to DID-PQ (total possible N = 310)
  3. b Includes DID-PQ responses of “strongly prefer dulaglutide” and “prefer dulaglutide”
  4. c Includes DID-PQ responses of “strongly prefer semaglutide” and “prefer semaglutide”
  5. d The p-values are from a two-sided binomial test for each DID-PQ item to determine whether significantly more participants preferred one device over the other. This test assessed whether the proportion of patients indicating preference for one of the two devices differed from 0.5. A significant p-value means that significantly more participants preferred one device over the other. Patients with no preference between devices were excluded from this analysis