Table 4 Concept Comparison across Literature and Patient Report
From: Development of the neurotrophic keratopathy questionnaire: qualitative research
Concept | Reported in Literature: NK | Reported in Literature: Related Conditionsa | Spontaneous | Probed | Total (N = 14) N, % | Item in NKQ |
|---|---|---|---|---|---|---|
Redness | X | X | 0 | 12 (86%) | 12 (86%) | 5 |
Sensitivity to light (photophobia) | NR | X | 6 (43%) | 5 (36%) | 11 (79%) | 7 |
General discomfort | X | X | 2 (14%) | 7 (50%) | 9 (64%) | 6 |
Dryness | X | X | 3 (21%) | 6 (43%) | 9 (64%) | 3 |
Reduction in visual acuity | X | X | 6 (43%) | 3 (21%) | 9 (64%) | 1 |
Blurred vision (or glare disability) | NR | X | 4 (29%) | 4 (29%) | 8 (57%) | 2 |
Burning or stinging | NR | X | 0 | 5 (36%) | 5 (36%) | 4 |
Irregular blinking | X | X | 0 | 1 (7%) | 1 (7%) | 8 |
Decreased corneal sensationb (hypoesthesia or anesthesia) | X | X | NA | NA | NA | 9 |
Increased or decreased tear productionc | X | X | NA | NA | NA | 10 |
Tearing (watery eyes)c | NR | X | NA | NA | NA | 11 |
Pain or discomfort (acute, chronic, or prodromal)d | X | X | 1 (7%) | 2 (14%) | 3 (21%) | None |
Ocular fatiguee | NR | X | 0 | 8 (57%) | 8 (57%) | None |
Irritation or sorenesse | NR | X | 2 (14%) | 5 (36%) | 7 (50%) | None |
Itching (scratchiness)e | NR | X | 0 | 7 (50%) | 7 (50%) | None |
Foreign body sensation (sand, grit in eye)e | NR | X | 0 | 6 (43%) | 6 (43%) | None |
Inflammation (swelling of eye and/or eyelid)e | X | X | 1 (7%) | 3 (21%) | 4 (29%) | None |
Forced closing of eyelidse | NR | X | 0 | 2 (14%) | 2 (14%) | None |
Dischargee | NR | X | 1 (7%) | 1 (7%) | 2 (14%) | None |
Headachese | NR | NR | 0 | 2 (14%) | 2 (14%) | None |
Sores or rash around the eyese | NR | X | 0 | 1 (7%) | 1 (7%) | None |
Cutaneous blisteringe | NR | X | 0 | 1 (7%) | 1 (7%) | None |
Punched-out oval or circular shapee | NR | X | 0 | 0 | 0 (0%) | None |
Sensitivity to coldf | NR | NR | 1 (7%) | 0 | 1 (7%) | None |
Increased optic pressuref | NR | NR | 1 (7%) | 0 | 1 (7%) | None |
Bleedingf | NR | NR | 1 (7%) | 0 | 1 (7%) | None |
Decreased peripheral visionf | NR | NR | 1 (7%) | 0 | 1 (7%) | None |
Floatersf | NR | NR | 1 (7%) | 0 | 1 (7%) | None |