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Table 1 Axillary Hyperhidrosis Patient Measures (AHPM)

From: Development and validation of the Axillary Sweating Daily Diary: a patient-reported outcome measure to assess axillary sweating severity

Axillary Sweating Daily Diary (ASDD)a

Instructions: The questions in the diary are designed to measure the severity and impact of any underarm sweating you have experienced within the previous 24-h period, including nighttime hours. While you may also experience sweating in other locations on your body, please be sure to think only about your underarm sweating when answering these questions.

Please complete the diary each evening before you go to sleep.

Item 1 [Gatekeeper]

During the past 24 h, did you have any underarm sweating?

Yes/No

When Item 1 is answered “no,” Item 2 is skipped and scored as zero

Item 2

During the past 24 h, how would you rate your underarm sweating at its worst?

0 (no sweating at all) to 10 (worst possible sweating)

Item 3

During the past 24 h, to what extent did your underarm sweating impact your activities?

0 (not at all), 1 (a little bit), 2 (a moderate amount), 3 (a great deal), 4 (an extreme amount)

Item 4

During the past 24 h, how bothered were you by your underarm sweating? 0 (not at all bothered), 1 (a little bothered), 2 (moderately bothered), 3 (very bothered), 4 (extremely bothered)

Axillary Sweating Daily Diary-Children (ASDD-C)b

Instructions: These questions measure how bad your underarm sweating was last night and today. Please think only about your underarm sweating when answering these questions.

Please complete these questions each night before you go to sleep.

Item 1 [Gatekeeper]

Thinking about last night and today, did you have any underarm sweating?

Yes/No

When Item 1 is answered “no,” Item 2 is skipped and scored as zero

Item 2

Thinking about last night and today, how bad was your underarm sweating? 0 (no sweating at all) to 10 (worst possible sweating)

Weekly Impact Itemsa

Instructions: Please respond “Yes” or “No” to each of the following questions.

 a. During the past 7 days, did you ever have to change your shirt during the day because of your underarm sweating?

Yes/No

 b. During the past 7 days, did you ever have to take more than 1 shower or bath a day because of your underarm sweating?

Yes/No

 c. During the past 7 days, did you ever feel less confident in yourself because of your underarm sweating?

Yes/No

 d. During the past 7 days, did you ever feel embarrassed by your underarm sweating?

Yes/No

 e. During the past 7 days, did you ever avoid interactions with other people because of your underarm sweating?

Yes/No

 f. During the past 7 days, did your underarm sweating ever keep you from doing an activity you wanted or needed to do?

Yes/No

Patient Global Impression of Change (PGIC) Itema

Overall, how would you rate your underarm sweating now as compared to before starting the study treatment?

1 (much better), 2 (moderately better), 3 (a little better), 4 (no difference), 5 (a little worse), 6 (moderately worse), 7 (much worse)

  1. a For use in patients ≥16 years of age
  2. b For use in patients ≥9 to < 16 years of age
  3. Copyright© Dermira, Inc. 2017