Evaluation of the psychometric properties and minimally important difference of the MD Anderson Symptom Inventory for malignant pleural mesothelioma (MDASI-MPM)

Journal of Patient-Reported Outcomes

Table 1 Assessment schedule and the number of respondents at each timepoint

Assessment	MDASI-MPM	LCSS-Meso	ECOG PS
Screening/baseline^a	239	239	239
Cycle 1 Day 1	0	0	234
Cycle 1 Day 8	164	0	0
Cycle 1 Day 15	153	0	0
Cycle 2 Day 1^b	210	201	214
Cycle 2 Day 8	157	0	0
Cycle 2 Day 15	156	0	0
Cycle 3 Day 1^b	167	164	173
Cycle 3 Day 8	119	0	0
Cycle 3 Day 15	108	0	0
Cycle 4 Day 1	135	132	140
Cycle 5 Day 1	112	110	117
Cycle 6 Day 1	90	90	91
Safety follow-up^a	103	101	117

^aTests for sensitivity were performed between baseline and safety follow-up
^bTests for stability were conducted between Cycle 2 Day 1 and Cycle 3 Day 1
Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status, LCSS-Meso Lung Cancer Symptom Scale-Mesothelioma, MDASI-MPM MD Anderson Symptom Inventory for malignant pleural mesothelioma