Journal of Patient-Reported Outcomes

Table 4 Changes in Average 7-Day ASD Score by ACQ Change Groups at Weeks 12 and 24

From: Evaluating minimal important differences and responder definitions for the asthma symptom diary in patients with moderate to severe asthma

ACQ Group	Week 12	Week 24
1 Change ≤ −1.0 [Responder]	−0.54	−0.68
2 Change −0.5 to −1.0 [MID]	−0.35	−0.35
3 Change ≥ −0.5	− 0.05	− 0.05
Model p-value	< 0.0001	< 0.0001
Significant contrasts (p < 0.01)	1v2; 1v3; 2v3	1v2; 1v3; 2v3

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