Skip to main content

Advertisement

Table 4 Clinically important difference (CID) and responder definition (RD) estimations for FACIT-Fatigue in patients with PsA

From: RETRACTED ARTICLE: Content validity and psychometric evaluation of Functional Assessment of Chronic Illness Therapy-Fatigue in patients with psoriatic arthritis

Model Analysis Anchor Study data Experience domain Impact domain Total score
  Clinically important difference (SE) [95% CI]
Repeated measures model-CID Main analysis PtGA Pooled 1.45 (0.04) 1.73 (0.05) 3.12 (0.08)
[1.38, 1.52] [1.63, 1.82] [2.97, 3.27]
Sensitivity analysis PtGA OPAL Broaden 1.39 (0.05) 1.66 (0.06) 3.00 (0.10)
[1.30, 1.48] [1.53, 1.78] [2.80, 3.19]
OPAL Beyond 1.53 (0.06) 1.82 (0.08) 3.29 (0.12)
[1.42, 1.64] [1.67, 1.97] [3.04, 3.53]
SF-36 Vitality Pooled 1.06 (0.01) 1.21 (0.02) 2.25 (0.03)
[1.03, 1.08] [1.17, 1.25] [2.18, 2.31]
  Effect size (SD)
Repeated measures model-CID Main analysis PtGA Pooled 8.73 (4.54) 18.93 (6.88) 27.66 (10.95)
Sensitivity analysis PtGA OPAL Broaden 9.13 (4.34) 19.56 (6.57) 28.69 (10.47)
   OPAL Beyond 8.30 (4.72) 18.25 (7.14) 26.54 (11.35)
  Responder definition (SE) [95% CI]
Repeated measures model-RD Main analysis SGIC Pooled 1.67 (0.09) 2.12 (0.12) 3.76 (0.20)
[1.49, 1.86] [1.88, 2.37] [3.37, 4.15]
Sensitivity analysis OPAL Broaden 1.54 (0.12) 2.02 (0.15) 3.52 (0.25)
[1.31, 1.77] [1.72, 2.33] [3.03, 4.01]
OPAL Beyond 1.91 (0.16) 2.30 (0.20) 4.19 (0.33)
[1.60, 2.23] [1.90, 2.70] [3.54, 4.85]
  1. Pooled data: OPAL Broaden and OPAL Beyond
  2. CI confidence interval, CID clinically important difference; FACIT-Fatigue Functional Assessment of Chronic Illness Therapy–Fatigue; PsA psoriatic arthritis, PtGA Patient’s Global Assessment of Psoriasis and Arthritis, RD responder definition, RMM repeated measures model, SD standard deviation, SE standard error, SF-36 Short Form Survey-36, SGIC Subject Global Impression of Change