Databases + Search strategy
# References Screened
# Articles reviewed
Howell et al. 2015 
To identify PROMs used in routine cancer clinical practice, their impact on patient, provider, and system outcomes, and the implementation factors influencing uptake.
Ovid Medline CINAHL PsycINFO Grey Literature
The EORTC QLQ30 was the most commonly used PRO Use of PROMs for screening for emotional distress, unmet supportive care needs, or social difficulties Wide variety of PROMs were used with little standardization across studies PROMs implementation improves communication about symptoms and QoL More attention needs to be paid to complexity of implementation and interpretation of PROMS
King et al. 2016 
To examine the use and impact of using quality of life measures on health care of cancer patients within a clinical setting, particularly those with brain cancer.
PubMed, EMBASE, Cochrane (SR & Trials), Web of Science [SCI]) Grey literature
QoL data may improve patient–physician communication, increase discussion of emotional functioning in particular. Scarcity of data on actions/medical decisions.
Chen et al. 2013 
To provide a comprehensive review update including all relevant quantitative studies investigating the effectiveness of routine PRO collection in cancer patients.
NR Two-step search strategy building on existing reviews
Strong evidence: PROs enhances patient-provider communication, improves patient satisfaction.
Moderate evidence: PRO improves monitoring of treatment response and the detection of unrecognized problems.
Weak Evidence: Changes to patient management, improved health outcomes
No evidence: changes to patient health behavior, quality improvement, increased transparency, accountability, public reporting and better health care system performance
Jensen et al. 2013 
To identify existing PRO systems and their administration of PRO assessments, integration of information into the clinic workflow and EHR systems, and the reporting of PRO information.
190 plus conference abstracts and gray literature
33 ePRO systems reviewed
Not specified, conferences 2009–2011
Identified systems were generally developed to improve symptom management, identify psychosocial problems, and facilitate patient-provider communication.
Data on actual impact was not part of review scope
Antunes et al. 2014 
To systematically identify facilitators and barriers to the implementation of patient-reported outcome measures in different palliative care settings for routine practice
Medline, PsycINFO, Cumulative Index to Nursing Allied Health Literature,
British Nursing Index
There is a need for guidance on implementing PROMs in palliative care clinical practice.
Alsaleh 2013 
To review the scientific evidence behind recommending the use of QoL scales routinely in outpatient evaluation.
Medline, Embase, PsycINFO
Evidence for the use of QoL scales in daily clinical practice is limited. Some weak evidence suggesting that this might improve communication between patients and health caregivers.
No good evidence that routine administration of QoL questionnaires improve patient’s QoL or changes management.
The overall impression is that routine administration of questionnaires in medical oncology outpatient clinics is currently hardly justified.
Luckett et al. 2009 
To identify future strategies for PRO interventions to impact patient outcomes in cancer clinics
References from earlier review included
More trials are urgently needed to build a satisfactory evidence base for the routine clinical use of patient-reported data in oncology.
Evidence for improvement in patient outcomes as result of PROM use has been limited
Kotronoulas et al. 2014 
Is inclusion of PROM in routine clinical practice associated with improvements in patient outcomes, processes of care, and health service outcomes during active anticancer treatment
Medline, EMBASE, CINAHL, PsycINFO, PBSC
Database inception −2012
Use of PROMs increases the frequency of discussion of patient outcomes. Some support for positive association between use of PROSM and improved symptom control, increased supportive care measures, and patient satisfaction. Need for additional effort to ensure patient adherence and clear system guidelines to guide clinicians response. More research needed to support cost-benefit.
Yang et al. 2017 
To identify mechanisms through which
PROs facilitate patient-clinician communication in the adult
EMBASE, CINAHL, PsycINFO, Cab Direct, CDSR
Prior to 2016
PROs facilitate patient-clinician communication through various mechanisms that could perhaps contribute to improvements in symptom management
and survival. The impact of PROs on clinical outcomes, however, remains poorly studied.
Bouazzaa et al. 2017 
To analyze the use of PROMs in the treatment of lung cancer with the aim
of improving the quality of care.
The secondary objective is to evaluate PROMS currently being used in the care of lung cancer.
Web of Science and Google Scholar
There has yet to be a study on the routine implementation of lung cancer specific PROMs, but PROMs have a promising role.