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Table 1 Sample and study design characteristics of selected records

From: Psychometric validation of the work productivity and activity impairment questionnaire in ulcerative colitis: results from a systematic literature review

Study Article/ poster Study design Sample description Disease status WPAI version
Cohen 2014 [30] Article Cross-sectional 220 patients with IBD (95 with UC) enrolled in a patient registry in the US in 2008–2009 Mixed (75% remission, 25% active) WPAI:GH
Gibson 2014 [31] Article Cross-sectional 175 outpatients with UC attending specialist consultations in Australia in 2011 Mixed (54% remission, 46% active [17% mild, 30% moderate/severe]) WPAI:UC
Mandel 2014 [32] Article Cross-sectional 443 patients with IBD (183 with UC) at specialized IBD centers in Hungary Mixed (75% remission, 25% active) WPAI:UC
Meijs 2014 [33] Article Cross-sectional 58 inpatients with UC that were hospitalized in the Netherlands in 2008–2011 Remission (50% medication, 50% post-surgical) WPAI:UC
Travis 2017 [29] Article Open-label non-comparative interventional 463 patients with UC from 92 study sites in Europe, Asia, and North America in 2012-2015 All active at study baseline (moderate/severe) WPAI:GH
Vaizey 2014 [34] Article Cross-sectional 173 outpatients with UC visiting a gastroenterologist in the UK in 2011–2012 Mixed (58% remission, 42% active [18% mild, 24% moderate/severe]) WPAI:UC
van Assche 2016 [35] Article Cross-sectional 253 patients with UC recruited at investigative sites from 11 European countries Mixed (20% remission, 80% active) WPAI:UC
Yarlas 2015a [36] Article Open-label non-comparative interventional 309 patients with UC recruited at investigative sites from the US in 2007–2009 All active at acute phase baseline, all in remission at maintenance phase baseline WPAI:UC
Jackson 2016 [38] Poster Cross-sectional 81 patients with IBD (31 with UC) attending a tertiary clinic in Australia in 2015 Mixed (NOS) WPAI:GH
Katz Avitan 2016 [39] Poster Cross-sectional 405 patients with IBD (150 with UC) attending a tertiary hospital in Israel 2015 Mixed (67% remission, 33% active) WPAI:UC
Willshire 2014 [40] Poster Open-label non-comparative interventional 717 patients with UC recruited at investigative sites globally All active at acute phase baseline, all in remission at maintenance phase baseline WPAI:UC
Yarlas 2014 [41] Poster Open-label non-comparative interventional 717 patients with UC recruited at investigative sites globally All active at acute phase baseline, all in remission at maintenance phase baseline WPAI:UC
Yarlas 2015b [37] Poster Open-label non-comparative interventional 717 patients with UC recruited at investigative sites globally All active at acute phase baseline, all in remission at maintenance phase baseline WPAI:UC
  1. GH general health, IBD inflammatory bowel disease, NOS not otherwise specified UC ulcerative colitis, UK United Kingdom, US United States, WPAI Work Productivity and Activity Impairment questionnaire