Baseline | Week 8 | Change | |||||
---|---|---|---|---|---|---|---|
N | LS Mean | SE | LS Mean | SE | LS Mean Difference (95% CI) | Effect size dz, (95% CI) | |
SF-12v2 | |||||||
Physical functioning | 673 | 46.3 | 0.36 | 51.0 | 0.34 | 4.6‡ (3.7, 5.6) | 0.41 (0.32, 0.49) |
Role physical | 673 | 43.8 | 0.32 | 49.4 | 0.30 | 5.6‡ (4.7, 6.5) | 0.61 (0.52, 0.70) |
Bodily pain | 673 | 43.5 | 0.37 | 51.6 | 0.33 | 8.1‡ (7.2, 9.1) | 0.74 (0.63, 0.83) |
General health | 674 | 41.6 | 0.40 | 48.8 | 0.37 | 7.3‡ (6.2, 8.3) | 0.63 (0.54, 0.73) |
Vitality | 672 | 46.8 | 0.38 | 53.2 | 0.39 | 6.4‡ (5.3, 7.5) | 0.53 (0.43, 0.61) |
Social functioning | 674 | 42.5 | 0.37 | 49.2 | 0.35 | 6.8‡ (5.8, 7.8) | 0.63 (0.53, 0.71) |
Role emotional | 673 | 41.9 | 0.38 | 47.5 | 0.37 | 5.6‡ (4.6, 6.6) | 0.49 (0.39, 0.58) |
Mental health | 674 | 44.2 | 0.38 | 50.8 | 0.39 | 6.6‡ (5.5, 7.6) | 0.56 (0.47, 0.65) |
PCS | 673 | 44.9 | 0.31 | 50.8 | 0.28 | 5.9‡ (5.1, 6.8) | 0.65 (0.55, 0.74) |
MCS | 674 | 43.2 | 0.37 | 49.5 | 0.36 | 6.4‡ (5.3, 7.4) | 0.58 (0.49, 0.66) |
SIBDQ | |||||||
Bowel symptoms | 602 | 12.6 | 0.13 | 16.7 | 0.15 | 4.1‡ (3.7, 4.5) | 1.00 (0.88, 1.10) |
Systemic symptoms | 602 | 8.9 | 0.11 | 10.9 | 0.11 | 2.0‡ (1.7, 2.3) | 0.68 (0.57, 0.77) |
Emotional function | 602 | 12.8 | 0.17 | 16.1 | 0.17 | 3.2‡ (2.8, 3.7) | 0.74 (0.64, 0.86) |
Social function | 601 | 9.0 | 0.13 | 11.6 | 0.12 | 2.6‡ (2.3, 3.0) | 0.77 (0.66, 0.86) |
Total score | 600 | 43.3 | 0.45 | 55.3 | 0.49 | 12.0‡ (10.7, 13.3) | 0.92 (0.80, 1.02) |