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Journal of Patient-Reported Outcomes

Table 4 Multivariable regression analysis for continuous screener total and domains scores

From: Development and validation of fear of hypoglycemia screener: results from the T1D exchange registry

 

Screener-total

Screener-domains

Outcome variables

b

R2

b - worry

b - behavior

R2

Self-reported HbA1c (%)

0.04***

0.15

0.00

0.15***

0.21

Number of comorbidities

0.03**

0.33

0.01

0.06*

0.33

Comfortable BG range – low

0.56***

0.06

0.17

1.57***

0.07

Comfortable BG range – high

1.02***

0.04

-0.32

4.58***

0.09

Depression (PHQ-8)

0.27***

0.22

0.14**

0.63***

0.25

Anxiety (GAD-7)

0.31***

0.26

0.25***

0.46***

0.27

T1-DDS - hypo distress

0.11***

0.43

0.13***

0.06**

0.44

T1-DDS - management distress

0.06***

0.30

0.02**

0.16***

0.35

T1-DDS - powerlessness

0.08***

0.31

0.07***

0.11***

0.31

  1. b, unstandardized regression coefficient; BG, blood glucose; GAD-7, generalized anxiety disorder; HbA1c, glycated hemoglobin. PHQ-8, Patient Health Questionnaire-8; T1-DDS, Diabetes Distress Scale for Adults with Type 1 Diabetes. Adjusted for covariates: gender, age, duration of T1D, insulin pump use, and continuous glucose monitoring (CGM) use. The table shows the unstandardized regression coefficients (b) between the continuous screener scores and outcome variables, as well as adjusted R-square for each regression model. The unstandardized regression coefficients show the unit change in outcome variables providing one unit change in the predictor, i.e. total screener score and domain scores because the predictors were binary variables. Comfortable BG range (mg/dL) – low: 85 (40–250). Comfortable BG range (mg/dL) – high: 150 (90–600). *P < 0.05, **P < 0.01, ***P < 0.001
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