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Table 4 SIC Internal Consistency Reliabilities (Cross-sectional Study, N = 152; ENSEMBLE2 Trial, N = 130a)

From: Psychometric evaluation of the Symptoms of Infection with Coronavirus-19 (SIC): results from a cross-sectional study and a phase 3 clinical trial

SIC composite score

Cronbach’s alpha,b

cross-sectional study

Cronbach’s alpha,b ENSEMBLE2c

No. of items

Constitutional

0.72

0.71

6

Gastrointestinal

0.69

0.71

5

Musculoskeletal

0.86

0.82

3

Neurologic

0.72

0.41

3

Sensory

0.91

0.87

2

Respiratory

0.87

0.82

9

Upper respiratory

0.80

0.80

4

Lower respiratory

0.84

0.75

5

  1. COVID-19, coronavirus disease 2019; SIC, Symptoms of Infection with Coronavirus-19; PCR, polymerase chain reaction.
  2. aOf 183 participants with PCR-confirmed moderate to severe/critical COVID-19 occurring from Days 15 to 56 post–primary vaccination, 130 completed the SIC.
  3. bCronbach’s alpha ≥ 0.70 indicates a set of items that is strongly related.
  4. cSIC completed at Day 1 of a COVID-19 episode in ENSEMBLE2.