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Table 1 EQ-5D-5L utility values, WHODAS scores, and PROMIS scores stratified by select demographic and clinical characteristics

From: The health impact of long COVID: a cross-sectional examination of health-related quality of life, disability, and health status among individuals with self-reported post-acute sequelae of SARS CoV-2 infection at various points of recovery

Variable

N (%)

Median (IQR) utility value (n = 82)

Median (IQR) WHODAS score (n = 73)

Median (IQR) PROMIS PH score (n = 80)

Median (IQR) PROMIS MH score (n = 77)

Total

82 (100)

0.59 (0.42)

50.0 (27.1)

10.5 (4.0)

8.0 (4.0)

Time since onset of infection/symptoms

0–6 months

15 (18.3)

0.62 (0.81)

41.7 (31.3)

12.0 (6.0)

6.0 (5.0)

7–12 months

20 (24.4)

0.59 (0.31)

44.8 (25.0)

9.0 (4.0)

8.0 (6.0)

13–18 months

14 (17.1)

0.48 (0.35)

62.5 (20.9)

10.0 (3.0)

8.0 (5.0)

19+ months

20 (24.4)

0.59 (0.33)

53.2 (16.6)

11.0 (3.0)

8.0 (3.0)

Unknown/Missing*

13 (15.9)

0.62 (0.39)

47.9 (41.7)

11.5 (6.0)

9.5 (5.0)

Severity of acute COVID-19 infection

Asymptomatic

4 (4.9)

0.33 (0.56)

58.4 (30.3)

8.0 (3.0)

7.0 (4.5)

Mild

35 (42.7)

0.62 (0.51)

45.9 (33.3)

12.0 (5.0)

8.0 (5.5)

Moderate

36 (43.9)

0.53 (0.33)

52.1 (25.0)

10.0 (3.5)

8.0 (4.0)

Severe

3 (3.7)

0.60 (0.19)

37.5 (14.6)

11.0 (3.0)

9.0 (6.0)

Unknown/missing*

4 (4.9)

0.74 (0.29)

47.9 (39.5)

12.0 (2.0)

13.0 (6.0)

Gender

Women

44 (53.7)

0.59 (0.32)

52.1 (27.1)

10.0 (4.0)

8.5 (4.0)

Men

30 (36.6)

0.59 (0.50)

42.8 (33.4)

12.0 (4.0)

6.5 (5.0)

Unknown/missing*

8 (9.8)

0.60 (0.67)

47.9 (33.3)

10.0 (5.0)

8.0 (5.0)

Age

18–29

21 (25.3)

0.36 (0.53)

47.9 (31.3)

11.0 (5.0)

6.0 (5.5)

30–49

31 (37.4)

0.62 (0.19)

51.1 (25.0)

11.0 (3.0)

8.0 (3.0)

50+

19 (22.9)

0.59 (0.38)

50.0 (31.3)

9.0 (4.0)

9.0 (5.0)

Unknown/missing*

11 (14.5)

0.54 (0.67)

50.0 (12.5)

9.5 (5.0)

7.0 (4.0)

Education status

Less than Bachelor’s Degree

20 (24.4)

0.64 (0.30)

43.8 (27.1)

12.0 (6.0)

6.0 (4.0)

Bachelor’s Degree

35 (42.7)

0.56 (0.31)

52.1 (27.1)

10.0 (4.0)

8.5 (4.0)

Master’s or Doctorate

19 (23.2)

0.59 (0.50)

52.1 (33.3)

10.0 (4.0)

7.5 (5.0)

Unknown/Missing*

8 (9.8)

0.60 (0.67)

47.9 (33.3)

10.0 (5.0)

8.0 (5.0)

Geographic setting

Urban/suburban

57 (69.5)

0.56 (0.39)

52.1 (29.2)

10.5 (4.5)

8.0 (5.0)

Rural

15 (18.3)

0.60 (0.39)

51.1 (22.9)

10.0 (4.0)

8.0 (2.0)

Unknown/missing*

10 (12.2)

0.69 (0.67)

47.9 (29.1)

11.0 (4.0)

8.0 (4.0)

Insurance

Private

23 (28.1)

0.52 (0.35)

47.9 (20.9)

10.0 (3.0)

8.0 (5.0)

Government

17 (20.7)

0.56 (0.22)

53.2 (21.9)

11.0 (4.0)

8.0 (2.5)

Other Insurance

2 (2.4)

0.68 (0.19)

31.3 (33.3)

10.5 (7.0)

13.5 (5.0)

Uninsured

10 (12.2)

0.68 (0.22)

45.9 (29.2)

10.5 (5.0)

8.5 (3.0)

Unknown/missing*

33 (40.2)

0.60 (0.58)

51.1 (37.5)

11.0 (5.0)

7.5 (4.5)

BMI

 < 25

35 (42.7)

0.56 (0.60)

47.9 (31.3)

10.0 (4.0)

8.0 (5.0)

25 to < 30

13 (15.7)

0.58 (0.29)

46.9 (20.9)

12.0 (5.0)

8.0 (1.0)

30+

15 (18.1)

0.59 (0.32)

47.9 (20.8)

11.0 (5.0)

8.0 (5.0)

Unknown/missing*

19 (24.1)

0.63 (0.37)

52.1 (2.1)

10.0 (3.0)

8.0 (6.0)

Exercise per week (pre-COVID)

0 to < 2 h

19 (23.2)

0.59 (0.26)

43.8 (23.0)

11.0 (5.0)

8.0 (4.0)

2 to < 5 h

26 (31.7)

0.63 (0.43)

47.9 (27.1)

11.0 (2.0)

8.0 (5.0)

5+ hours

31 (37.8)

0.41 (0.51)

56.3 (24.0)

9.0 (4.0)

8.0 (5.0)

Unknown/missing*

6 (7.3)

0.76 (0.34)

35.5 (33.3)

11.0 (4.0)

8.0 (3.0)

COVID status

Confirmed

49 (59.8)

0.56 (0.45)

47.9 (25.0)

11.0 (5.0)

8.0 (5.0)

Suspected

33 (40.2)

0.59 (0.33)

52.1 (28.2)

10.0 (3.0)

9.0 (4.0)

Received COVID vaccine

Yes

71 (86.6)

0.58 (0.40)

52.1 (27.1)

10.0 (4.0)

8.0 (4.0)

No

10 (12.2)

0.63 (0.50)

41.7 (14.6)

11.5 (5.0)

7.5 (6.0)

Symptom count (previous 30 days)

 < 10

36 (43.9)

0.61 (0.40)

41.7 (27.1)

11.0 (4.0)

8.0 (6.0)

10–29

27 (32.9)

0.68 (0.43)

43.8 (18.8)

12.0 (4.0)

8.0 (4.0)

30+

19 (23.2)

0.44 (0.31)

62.5 (18.7)

8.0 (3.0)

8.0 (3.0)

Long COVID clinic

Yes

14 (18.4)

0.29 (0.65)

49.0 (29.2)

9.0 (3.0)

6.5 (3.0)

No

58 (76.3)

0.59 (0.39)

56.3 (27.0)

11.0 (4.0)

8.0 (5.0)

Medication use specific to long COVID

Yes

47 (57.3)

0.54 (0.46)

53.2 (25.0)

10.0 (4.0)

8.0 (5.0)

No

25 (30.5)

0.59 (0.31)

43.8 (25.0)

11.0 (5.0)

9.0 (5.0)

Unsure*

3 (3.7)

0.41 (0.24)

35.4 (14.6)

12.0 (3.0)

9.0 (10.0)

Unknown/missing*

7 (8.5)

0.78 (0.39)

35.4 (18.7)

11.0 (4.0)

  1. Utility values range from “0”, respresenting a health state equivalent to death, and “1”, representing “perfect health.” WHODAS scores range from “0” representing no disability and “100” representing full disability. PROMIS PH and MH Scores range from “4” to “20” with higher scores indicative of better health
  2. PH physical health, MH mental health, BMI body mass index
  3. *Unknown/missing/unsure categories were not used in the calculation of p values
  4. Significant at p < 0.05