| | Modified Cohort 1a | Cohort 2a | P-valueb |
|---|
n | Mean (SD) | n | Mean (SD) |
|---|
EQ-5D-5L scoresc |
Health state VAS | 446 | 70.4 (21.4) | 204 | 66.8 (25.1) | 0.2068 |
Utility score | 442 | 0.78 (0.18) | 197 | 0.71 (0.21) | 0.0163 |
SDS scoresd |
Work/school | 310 | 3.5 (3.4) | 111 | 4.2 (3.4) | 0.2559 |
Social life | 446 | 3.5 (3.2) | 203 | 4.0 (3.4) | 0.8237 |
Family/home life | 445 | 3.4 (3.2) | 203 | 3.8 (3.3) | 0.8449 |
Total score | 445 | 10.5 (8.8) | 203 | 11.7 (9.3) | 0.7245 |
- EQ-5D-5L EuroQoL 5-dimension 5-level questionnaire; SD standard deviation; SDS Sheehan Disability Scale; VAS visual analog scale
- aModified Cohort 1 includes patients with no visible or self-reported abnormal involuntary movements. Cohort 2 includes all patients with possible TD per clinician assessment
- bAdjusted for age, sex, overall health status, severity of psychiatric condition per clinician impression, functional status of patient per clinician impression, and psychiatric diagnosis
- cHigher EQ-5D-5L scores indicate better health-related quality of life: VAS (range, 0 = “worst health you can imagine” to 100 = “best health you can imagine”); utility (range, 0 = “health state equivalent to death” to 1 = “perfect health”)
- dHigher SDS scores indicate greater disruption due to health condition: domain scores (range, 0 = “not at all” [no disruption to work/school, social life, or family/home life] to 10 = “extremely” [extreme disruption]). Total scores (range, 0–30) were calculated for patients who had a score on ≥ 2 domains. When only 1 domain was missing, the average of the patient’s observed score was imputed
