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Table 5 Hemo-TEM item correlations (total population, n = 88)

From: Understanding treatment burden in hemophilia: development and validation of the Hemophilia Treatment Experience Measure (Hemo-TEM)

 

1a

1b

1c

1d

1e

2a

2b

3a

3b

3c

3d

3e

3f

1a diff good place to inject

1.000

            

1b diff put needle correctly

.718b

1.000

           

1c diff find good place

.553

.644

1.000

          

1d diff remembera

.077

.242

.240

1.000

         

1e diff exactly as instructeda

.242

.241

.390

.541

1.000

        

2a often postpone on purpose

.117

.186

.279

.203

.300

1.000

       

2b often postpone accidenta

-.118

.091

.068

.381

.341

.363

1.000

      

3a often soreness

.253

.153

.209

.090

.162

.230

.189

1.000

     

3b often physical discomfort

.295

.245

.306

.036

.254

.304

.234

.683

1.000

    

3c often pain

.270

.181

.233

.095

.200

.132

.290

.622

.685

1.000

   

3d often bruising

.384

.282

.359

-.077

.046

.194

.110

.452

.387

.510

1.000

  

3e often ruptured veins

.389

.310

.264

.082

.060

.100

-.028

.394

.364

.324

.412

1.000

 

3f often probs scarring

.384

.303

.304

.117

.182

.089

.174

.513

.479

.524

.467

.469

1.000

4a bother number steps

.267

.209

.324

.186

.283

.323

.259

.238

.290

.288

.337

.205

.287

4b bother amt of time to prepare/give

.268

.259

.341

.265

.348

.409

.295

.196

.081

.201

.312

.146

.207

4c bother store meds

.231

.211

.475

.068

.171

.377

.165

.231

.063

.115

.329

.139

.282

4d bother carry meds

.294

.302

.485

.219

.275

.327

.233

.277

.161

.265

.420

.199

.349

4e bother often give treatment

.311

.270

.339

.234

.236

.461

.212

.240

.193

.263

.306

.246

.347

4f bother find time

.280

.284

.479

.277

.308

.431

.243

.269

.223

.228

.316

.250

.395

5a interfere travel/vacation

.442

.416

.545

.139

.270

.349

.129

.258

.253

.242

.485

.329

.383

5b interfere social acts

.277

.258

.463

.166

.311

.428

.241

.345

.393

.336

.377

.200

.330

5c interfere daily acts

.218

.146

.332

.253

.374

.325

.193

.361

.350

.242

.182

.175

.277

5d interfere work/school

.253

.138

.383

.190

.301

.340

.133

.443

.307

.257

.250

.350

.231

6a often anxious

.295

.297

.404

.173

.273

.313

.234

.344

.519

.363

.471

.375

.328

6b often frustrated

.363

.266

.349

.141

.269

.297

.214

.310

.384

.311

.464

.317

.444

6c often stressed

.196

.104

.248

.139

.342

.395

.137

.224

.385

.275

.431

.184

.224

6d often embarrasseda

.069

.138

.340

.302

.319

.307

.340

.228

.332

.273

.372

.291

.279

6e often worried infection

.247

.046

.183

.143

.242

.131

.153

.327

.446

.448

.230

.250

.300

6f often worried develop inhibitor

.141

.040

.236

-.063

.109

.147

.163

.469

.534

.485

.309

.276

.362

6g often worried losing access vein

.597

.595

.531

.025

.210

.164

.001

.386

.453

.419

.470

.613

.514

 

4a

4b

4c

4d

4e

4f

5a

5b

5c

5d

4a bother number steps

1.000

         

4b bother amt of time to prepare/give

.679

1.000

        

4c bother store meds

.384

.527

1.000

       

4d bother carry meds

.280

.511

.690

1.000

      

4e bother often give treatment

.497

.578

.458

.544

1.000

     

4f bother find time

.357

.519

.597

.719b

.653

1.000

    

5a interfere travel/vacation

.385

.488

.627

.651

.550

.556

1.000

   

5b interfere social acts

.513

.451

.457

.497

.606

.497

.690

1.000

  

5c interfere daily acts

.410

.363

.325

.437

.507

.483

.587

.773b

1.000

 

5d interfere work/school

.372

.283

.379

.434

.389

.590

.530

.629

.702b

1.000

6a often anxious

.488

.393

.406

.379

.453

.407

.506

.506

.421

.318

6b often frustrated

.432

.499

.436

.489

.517

.494

.600

.513

.459

.317

6c often stressed

.417

.448

.370

.392

.439

.432

.516

.558

.430

.269

6d often embarrasseda

.423

.370

.428

.465

.355

.442

.455

.499

.491

.314

6e often worried infection

.253

.090

.115

.210

.153

.146

.230

.222

.198

.240

6f often worried develop inhibitor

.195

.112

.195

.200

.142

.212

.296

.312

.210

.333

6g often worried losing access vein

.315

.331

.277

.363

.391

.262

.495

.413

.289

.293

 

6a

6b

6c

6d

6e

6f

6g

6a often anxious

1.000

      

6b often frustrated

.696

1.000

     

6c often stressed

.666

.690

1.000

    

6d often embarrassed

.647

.528

.576

1.000

   

6e often worried infection

.369

.239

.283

.318

1.000

  

6f often worried develop inhibitor

.347

.259

.314

.297

.617

1.000

 

6g often worried losing access vein

.510

.468

.300

.247

.276

.393

1.000

  1. aItem dropped after item reduction
  2. bVery strong association (r > 0.70) between items