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Table 3 PROMs and their (sub)domains potentially assessing relevant PROs

From: Development of a set of patient reported outcome measures for patients with benign liver tumours and cysts: patient focus groups and systematic review

PROM

Items (n)

Relevant PROs

Other PROs

Anxiety

Pain

Fatigue

Limitations in daily life

SF-36

36

Mental health: 5

Bodily pain: 2

Vitality: 4

Physical functioning: 10

Role—physical: 4

Social functioning: 2

Role—emotional: 3

General health: 5

Health transition: 1

SF-12

12

Calm and peaceful: 1

Downhearted and blue: 1

Energy: 1

Moderate activities: 1

Climb several flights of stairs: 1

Accomplished less (physical): 1

Limited in kind of work: 1

Accomplished less (emotional): 1

Did work less careful: 1

Pain – interference: 1

Social limitations – time: 1

General health: 1

EQ-5D

5

Anxiety/depression: 1

Pain/discomfort: 1

Usual activities: 1

Mobility: 1

Self-care: 1

QLQ-C30

30

Pain: 2

Fatigue: 3

Physical functioning: 5

Role functioning:2

Emotional functioning: 4

Cognitive functioning: 2

Social functioning: 2

Global health: 2

Nausea and vomiting: 2

Dyspnea: 1

Insomnia: 1

Appetite loss: 1

Constipation: 1

Diarrhea: 1

Financial difficulties: 1

McGill

78

Pain: 78

PROMIS

NA

V1.0 Anxiety CAT

V1.1 Pain behaviour CAT

V1.0 Pain intensity (NRS)

V1.0 Fatigue CAT

V1.1 Pain Interference CAT

V1.2 Physical function CAT

V2.0 Physical function – Mobility CAT

V2.0 Ability to participate in social roles and activities CAT

V2.0 Satisfaction with social roles and activities CAT

NA

  1. If an item focused on impairment of functioning caused by anxiety, pain or fatigue, this was counted as “limitations in daily life” rather than “anxiety”, “pain” or “fatigue”
  2. EQ-5D = EuroQol Five Dimensions Health Questionnaire, McGill = McGill Pain Questionnaire, QLQ-C30 = Core Quality of Life questionnaire (by European Organisation for Research and Treatment of Cancer), SF-12 and SF-36 = Short Form Health Survey (with 12 and 36 questions, respectively)