| Stable on PGRSa | Stable on PGRCb |
---|
Urgency NRS score | Â | Â |
n | 642 | 202 |
Mean (SD) | Â | Â |
Screening | 6.1 (2.10) | – |
Baseline | 6.2 (2.16) | 6.3 (2.29) |
Week 4 | – | 6.0 (2.28) |
p valuec | 0.189 | 0.007 |
ICC(2,1) (95% CI)d | 0.89 (0.87, 0.90) | 0.76 (0.70, 0.82) |
- CI confidence interval, ICC intraclass correlation coefficient, NRS Numeric Rating Scale, PGRC Patient Global Rating of Change, PGRS Patient Global Rating of Severity, SD standard deviation
- aParticipants recording the same PGRS score at screening and baseline
- bParticipants recording no change on the PGRC at week 4
- cPaired t test
- dICC(2,1) was calculated from a linear mixed-effects model with random intercepts using Urgency NRS scores from the two time points included in the analysis. A value ≥ 0.70 was considered evidence of acceptable test–retest reliability. Confidence intervals were constructed according to Cappelleri and Ting (2002)