Exploring life engagement from the perspective of patients with major depressive disorder: a study using patient interviews

Journal of Patient-Reported Outcomes

Table 4 Summary of expert, PCA and patient relevance of IDS-SR items to life engagement

Item (original IDS-SR numbering)	Associated with life engagement?
Item (original IDS-SR numbering)	Expert^a	PCA^b	Patients^c
8. Response of your mood to good or desired events	✓	✓	✓
15. Concentration/decision making	✓	✓	✓
16. View of myself	✓	✓	✓
17. View of my future	✓	✓	✓
19. General interest	✓	✓	✓
20. Energy level	✓	✓	✓
21. Capacity for pleasure or enjoyment (excluding sex)	✓	✓	✓
22. Interest in sex	✓	✓	✓
23. Feeling slowed down	✓	✓	✓
29. Interpersonal sensitivity	✓	✓
5. Feeling sad		✓	✓
10. The quality of your mood		✓	✓
30. Leaden paralysis/physical energy		✓
6. Feeling irritable			✓
7. Feeling anxious or tense			✓

IDS-SR, Inventory of Depressive Symptomatology Self-Report; MDD, major depressive disorder; PCA, principal component analysis
^aItems selected by a panel of expert academic psychiatrists [25]
^bItems that clustered together in a PCA [25]
^cItems with a mean relevance score ≥ 3 (moderately to very relevant) as rated by patients with MDD