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Table 3 Diagnostic accuracy of legacy measures at established cut-points compared with diagnosis of Any Anxiety Disorder using the Structured Clinical Interview for DSM disorders (SCID)

From: Convergent and criterion validity of PROMIS anxiety measures relative to six legacy measures and a structured diagnostic interview for anxiety in cancer patients

Measure

Sensitivity

(95% CI)

Specificity

(95% CI)

PPV*

(95% CI)

NPV**

(95% CI)

Mild cut-points

        

PROMIS-A-CAT 55

.59

(.43–.76)

.79

(.70–.86)

.53

(.41–.65)

.83

.78–.89

PROMIS-A-SF 55

.67

(.50–.81)

.79

(.71–.87)

.56

(.44–.68)

.86

.80–.92

HADS-A possible

.62

(.47–.78)

.80

(.72–.88)

.55

(.40–.70)

.84

.77–.92

DASS-A mild

.39

(.23–.55)

.78

(.69–.86)

.40

(.24–.56)

.77

.68–.85

DASS-S mild

.27

(.13–41)

.94

(.88–.99)

.63

(.39–.86)

.76

.68–.84

GAD-7 mild

.68

(.54–.83)

.75

(.67–.84)

.52

(.38–.66)

.85

.78–.93

DT

.46

(.30–.62)

.78

(.70–.86)

.45

(.29–.61)

.79

.70–.87

PSYCH-6

.57

(.41–.73)

.85

(.78–.92)

.59

(.42–.75)

.84

.77–.92

Moderate cut-points

        

PROMIS-A-CAT 65

.19

(.08–.32)

.97

(.93–1.00)

.71

(.43–1.00)

.75

.73–.79

PROMIS-A-SF 55

.19

(.08–.33)

.97

(.93–1.00)

.71

(.44–1.00)

.75

.73–.79

HADS-A probable

.27

(.13–.41)

.94

(.89–.99)

.63

(.39–.86)

.77

.69–.84

DASS-A moderate

.33

(.18–.49)

.86

(.79–.93)

.48

(.28–.68)

.77

.69–.85

DASS-S moderate

.16

(.04–.28)

.95

(.90–.99)

.55

(.25–.84)

.74

.66–.82

GAD-7 moderate

.24

(.11–.38)

.95

(.90–.99)

.64

(.39–.89)

.76

.68–.83

Optimal Cut-point***

        

PROMIS-A-CAT 53

.81

(.68–.92)

.72

(.63–.81)

.54

(.45–.63)

.91

.84–.96

PROMIS-A-SF 53

.78

(.64–.92)

.70

(.61–.78)

.50

(.42–.60)

.89

.83–.95

  1. *PPV Positive Predictive Value; **NPV Negative Predictive Value
  2. *** Selected by maximising Youden’s index