Health-related quality of life and social determinants of health following COVID-19 infection in a predominantly Latino population

Case, Kathleen R.; Wang, Chen-Pin; Hosek, Meredith G.; Lill, Sarah F.; Howell, Alexandra B.; Taylor, Barbara S.; Bridges, James; MacCarthy, Daniel J.; Winkler, Paula; Tsevat, Joel

doi:10.1186/s41687-022-00473-8

Table 4 Multivariable regression analyses examining the associations between demographics, clinical characteristics, COVID-19 concerns and health-related quality of life domains

Variable	B estimate (SE)	p value
Health utility
Latino ethnicity	− 0.03 (0.04)	0.55
COVID-19 concerns
Financial	− 0.11 (− 0.03)	< 0.001
Interpersonal conflict	− 0.15 (0.05)	0.001
Adjusted R² = 0.10
Physical function
Latino ethnicity	− 0.14 (1.64)	0.93
Age	− 0.21 (0.04)	< 0.001
COVID-19 concerns
Financial	− 4.39 (1.24)	< 0.001
Adjusted R² = 0.12
Anxiety
Latino ethnicity	1.32 (1.81)	0.47
COVID-19 concerns
Health-related impacts	3.92 (1.44)	0.007
Financial	4.52 (1.39)	0.006
Interpersonal conflict	9.03 (2.02)	< 0.001
Adjusted R² = 0.18
Depression
Latino ethnicity	0.56 (1.81)	0.76
COVID-19 concerns
Financial	4.10 (1.39)	0.004
Interpersonal conflict	6.80 (2.00)	< 0.001
Adjusted R² = 0.09
Fatigue
Latino ethnicity	− 2.69 (2.04)	0.30
COVID-19 concerns
Financial	5.22 (1.57)	0.001
Interpersonal conflict	7.96 (2.26)	<.001
Adjusted R² = 0.13
Sleep disturbance
Latino ethnicity	1.35 (1.49)	0.36
COVID-19 concerns
Financial	3.45 (1.15)	0.003
Interpersonal conflict	6.08 (1.65)	< 0.001
Adjusted R² = 0.11
Social function
Latino ethnicity	1.40 (1.74)	0.42
Age	− 0.19 (0.05)	< 0.001
COVID-19 concerns
Financial	− 3.72 (1.34)	0.006
Interpersonal conflict	− 7.66 (1.93)	< 0.001
Adjusted R² = 0.14
Pain interference
Latino ethnicity	0.02 (1.82)	0.99
Age	0.20 (.05)	< 0.001
COVID-19 concerns
Financial	4.30 (1.42)	0.003
Education	− 3.37 (1.69)	0.05
Interpersonal conflict	4.93 (2.04)	0.02
Adjusted R² = 0.14
Cognitive function—abilities
Latino ethnicity	− 3.34 (1.59)	0.04
Months since diagnosis	− 0.58 (0.18)	0.002
COVID-19 concerns
Financial	− 2.80 (1.20)	0.02
Adjusted R² = 0.08

Significant findings are reported (p < .05; bold font), as well as the association between Latino ethnicity and each outcome

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