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Table 3 Signs and symptoms reported by patients with COVID-19 (n = 24)

From: Development of a novel patient-reported outcome measure to assess signs and symptoms of COVID-19

Symptom, n (%)

Spontaneous

Probed

Total

Respiratory

 Cough

21 (87.5)

1 (4.2)

22 (91.7)

 Chest congestion/mucus production

5 (20.8)

13 (54.1)

18 (75.0)

 Shortness of breath

9 (37.5)

7 (29.2)

16 (66.7)

 Nasal congestion

4 (16.7)

12 (50.0)

16 (66.7)

 Chest pain/pressure/tightness

9 (37.5)

5 (20.8)

14 (58.3)

 Runny nose

7 (29.2)

6 (25.0)

13 (54.1)

 Sneezing

2 (8.3)

10 (41.7)

12 (50.0)

 Sore throat

6 (25.0)

6 (25.0)

12 (50.0)

 Wheezing

1 (4.2)

8 (33.3)

9 (37.5)

 Mucus in throat

5 (20.1)

3 (12.5)

8 (33.3)

 Coughing up blood

0 (0.0)

0 (0.0)

0 (0.0)

Musculoskeletal

 Muscle aches and pains

10 (41.7)

10 (41.7)

20 (83.3)

 Physical weakness

6 (25.0)

14 (58.3)

20 (83.3)

 Joint aches and pains

3 (12.5)

10 (41.7)

13 (54.2)

Neurological

 Headache

9 (37.5)

12 (50.0)

21 (87.5)

 Loss of smell

9 (37.5)

7 (29.2)

16 (66.7)

 Loss of taste

8 (33.3)

8 (33.3)

16 (66.7)

 Confusion or “brain fog”

2 (8.3)

12 (50.0)

14 (58.3)

 Fainting or feeling faint

1 (4.2)

10 (41.7)

11 (45.8)

 Dizziness

1 (4.2)

5 (20.8)

6 (25.0)

 Numbness or weakness in arms, hands, or face

2 (8.3)

4 (16.7)

6 (25.0)

 Difficulty speaking

0 (0.0)

1 (4.2)

1 (4.2)

 Difficulty understanding speech

0 (0.0)

1 (4.2)

1 (4.2)

Constitutional

 Fatigue/tiredness

14 (58.3)

9 (37.5)

23 (95.8)

 Feeling generally unwell/rundown

6 (25.0)

15 (62.5)

21 (87.5)

 Fever

14 (58.3)

5 (20.1)

19 (79.2)

 Chills

3 (12.5)

13 (54.2)

16 (66.7)

 Uncontrollable body shaking/shivering

1 (4.2)

6 (25.0)

7 (29.2)

 Skin rash

3 (12.5)

4 (16.7)

7 (29.2)

 Eye irritation/discharge

1 (4.2)

3 (12.5)

4 (16.7)

 Bluish lips/face/extremities

0 (0.0)

2 (8.3)

2 (8.3)

Gastrointestinal

 Loss of appetite

6 (25.0)

12 (50.0)

18 (75.0)

 Diarrhea

5 (20.8)

9 (37.5)

14 (58.3)

 Nausea

4 (16.7)

6 (25.0)

10 (41.2)

 Abdominal pain

0 (0.0)

8 (33.3)

8 (33.3)

 Vomiting

1 (4.2)

4 (16.7)

5 (20.1)

Cardiovascular

 Pain, swelling, or redness in legs

0 (0.0)

7 (29.2)

7 (29.2)

 Bruised looking feet or toes

0 (0.0)

4 (16.7)

4 (16.7)

Other

 Difficulty sleeping

9 (37.5)

NA

9 (37.5)

 Visual disturbance

1 (4.2)

NA

1 (4.2)

 Liver and kidney pain

1 (4.2)

NA

1 (4.2)

  1. Abbreviations: COVID-19 coronavirus disease 2019, NA not applicable