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Table 3 Signs and symptoms reported by patients with COVID-19 (n = 24)

From: Development of a novel patient-reported outcome measure to assess signs and symptoms of COVID-19

Symptom, n (%) Spontaneous Probed Total
Respiratory
 Cough 21 (87.5) 1 (4.2) 22 (91.7)
 Chest congestion/mucus production 5 (20.8) 13 (54.1) 18 (75.0)
 Shortness of breath 9 (37.5) 7 (29.2) 16 (66.7)
 Nasal congestion 4 (16.7) 12 (50.0) 16 (66.7)
 Chest pain/pressure/tightness 9 (37.5) 5 (20.8) 14 (58.3)
 Runny nose 7 (29.2) 6 (25.0) 13 (54.1)
 Sneezing 2 (8.3) 10 (41.7) 12 (50.0)
 Sore throat 6 (25.0) 6 (25.0) 12 (50.0)
 Wheezing 1 (4.2) 8 (33.3) 9 (37.5)
 Mucus in throat 5 (20.1) 3 (12.5) 8 (33.3)
 Coughing up blood 0 (0.0) 0 (0.0) 0 (0.0)
Musculoskeletal
 Muscle aches and pains 10 (41.7) 10 (41.7) 20 (83.3)
 Physical weakness 6 (25.0) 14 (58.3) 20 (83.3)
 Joint aches and pains 3 (12.5) 10 (41.7) 13 (54.2)
Neurological
 Headache 9 (37.5) 12 (50.0) 21 (87.5)
 Loss of smell 9 (37.5) 7 (29.2) 16 (66.7)
 Loss of taste 8 (33.3) 8 (33.3) 16 (66.7)
 Confusion or “brain fog” 2 (8.3) 12 (50.0) 14 (58.3)
 Fainting or feeling faint 1 (4.2) 10 (41.7) 11 (45.8)
 Dizziness 1 (4.2) 5 (20.8) 6 (25.0)
 Numbness or weakness in arms, hands, or face 2 (8.3) 4 (16.7) 6 (25.0)
 Difficulty speaking 0 (0.0) 1 (4.2) 1 (4.2)
 Difficulty understanding speech 0 (0.0) 1 (4.2) 1 (4.2)
Constitutional
 Fatigue/tiredness 14 (58.3) 9 (37.5) 23 (95.8)
 Feeling generally unwell/rundown 6 (25.0) 15 (62.5) 21 (87.5)
 Fever 14 (58.3) 5 (20.1) 19 (79.2)
 Chills 3 (12.5) 13 (54.2) 16 (66.7)
 Uncontrollable body shaking/shivering 1 (4.2) 6 (25.0) 7 (29.2)
 Skin rash 3 (12.5) 4 (16.7) 7 (29.2)
 Eye irritation/discharge 1 (4.2) 3 (12.5) 4 (16.7)
 Bluish lips/face/extremities 0 (0.0) 2 (8.3) 2 (8.3)
Gastrointestinal
 Loss of appetite 6 (25.0) 12 (50.0) 18 (75.0)
 Diarrhea 5 (20.8) 9 (37.5) 14 (58.3)
 Nausea 4 (16.7) 6 (25.0) 10 (41.2)
 Abdominal pain 0 (0.0) 8 (33.3) 8 (33.3)
 Vomiting 1 (4.2) 4 (16.7) 5 (20.1)
Cardiovascular
 Pain, swelling, or redness in legs 0 (0.0) 7 (29.2) 7 (29.2)
 Bruised looking feet or toes 0 (0.0) 4 (16.7) 4 (16.7)
Other
 Difficulty sleeping 9 (37.5) NA 9 (37.5)
 Visual disturbance 1 (4.2) NA 1 (4.2)
 Liver and kidney pain 1 (4.2) NA 1 (4.2)
  1. Abbreviations: COVID-19 coronavirus disease 2019, NA not applicable