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Table 1 MADRS severity criteria

From: Assessing the meaningful change threshold of Quality of Life in Depression Scale using data from two phase 3 studies of esketamine nasal spray

Criteria #1 and cut-off values [42] Criteria #2 and cut-off values [41] Criteria #3 and cut-off values [40]
No depression (0–12) No depression (0–6) No depression (0–12)
Slight depression (13–21) Slight depression (7–19) Slight depression (13–17)
Moderate depression (22–28) Moderate depression (20–34) Moderate depression (18–34)
Severe depression (> 28–60) Severe depression (> 34–60) Severe depression (> 34–60)
  1. MADRS Montgomery–Åsberg Depression Rating Scale