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Table 6 Longitudinal correlations with change in QOLPAD from baseline to follow-up (sensitivity to change)

From: Development and validation of a disease-specific quality of life questionnaire for patients with peripheral artery disease (QOLPAD)

 

r

p

n

Mean

Median

Minimum

Maximum

Δ EQ-5D-3L

 − 0.50

 < 0.001

51

0.18*

0.12

 − 0.36

91.2

Δ EQ VAS

 − 0.57

 < 0.001

50

10.5

10.0

 − 40.0

90.0

Δ VascuQoL

 − 0.72

 < 0.001

52

1.1

1.0

 − 1.2

4.5

Δ Stage of PAD

0.46

 < 0.001

46

1.0*

1.0

 − 2

4

Δ Global rating of impairment

0.64

 < 0.001

50

1.3*

1.0

 − 1

4

Global rating of symptom improvement

 − 0.55

 < 0.001

51

1.7*

1.0

1

4

Global rating of treatment effectiveness

0.46

0.001

51

2.8*

3.0

0

4

Global rating of recommendation of treatment

0.47

0.001

51

3.2*

4.0

0

4

  1. Baseline: first measurement, follow-up: second measurement, approximately 3 months after treatment, r: Spearman’s correlation coefficient, p: level of significance, n: number of patients; EQ VAS: EuroQol visual analogue scale, VascuQoL: Vascular Quality of Life Questionnaire, PAD: peripheral artery disease
  2. The stage of PAD was classified according to Fontaine, with 1–5 denoting stage I–IV, respectively [3]
  3. *Variables not normally distributed