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Table 1 Key asthma symptoms and impacts identified for measurement from the literature review and expert clinician interviews

From: Development and content validation of a self-completed, electronic Pediatric Asthma Symptom Diary

Symptom or Impact

Literature review

EC interviews

Primary asthma symptoms (daytime and nighttime)

 Cough

 Wheeze

 Difficulty breathing

 Chest tightness/discomfort

 

Proximal impacts

 Nighttime awakening

a

 Physical and social activity limitations (exercise, running, playing, sports)

 Rescue medication use

 

Distal impacts

 Fatigue and lack of concentration (as result of disturbed sleep due to nighttime symptoms)

 

 Lateness/absenteeism from school

 Lower productivity at school

 

 Missed social events

 Health-related quality of life

 
  1. EC expert clinician
  2. aNighttime awakening due primarily to cough and difficulty breathing were identified in the literature; nighttime awakening due to difficulty breathing, cough, and wheezing were primary symptoms reported by patients and/or caregivers to the expert clinicians interviewed