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Table 1 Key asthma symptoms and impacts identified for measurement from the literature review and expert clinician interviews

From: Development and content validation of a self-completed, electronic Pediatric Asthma Symptom Diary

Symptom or Impact

Literature review

EC interviews

Primary asthma symptoms (daytime and nighttime)

 Cough

âś“

âś“

 Wheeze

âś“

âś“

 Difficulty breathing

âś“

âś“

 Chest tightness/discomfort

âś“

 

Proximal impacts

 Nighttime awakening

âś“a

âś“

 Physical and social activity limitations (exercise, running, playing, sports)

âś“

âś“

 Rescue medication use

 

âś“

Distal impacts

 Fatigue and lack of concentration (as result of disturbed sleep due to nighttime symptoms)

âś“

 

 Lateness/absenteeism from school

âś“

âś“

 Lower productivity at school

âś“

 

 Missed social events

âś“

âś“

 Health-related quality of life

âś“

 
  1. EC expert clinician
  2. aNighttime awakening due primarily to cough and difficulty breathing were identified in the literature; nighttime awakening due to difficulty breathing, cough, and wheezing were primary symptoms reported by patients and/or caregivers to the expert clinicians interviewed