Table 1 Definitions of (A) calmness and (B) life engagement in major depressive disorder
A Patient-reported improvement codes related to calmness | ||
Aggravated (less) | Frustration (less) | Peaceful (more) |
Aggressive (less) | Hostility (less) | Physical tightness/stiffness (less) |
Agitated (less) | Impulsivity (less) | Relaxed (more) |
Anger (less) | Irritability (less) | Restlessness (less) |
Anxiety (less) | Knot in chest/stomach (resolved) | Shakiness (less) |
At ease (more) | Mellow (more) | Sit still (improved) |
Calm (more) | Nervousness (less) | Stress/stressed over things (less) |
Edginess (less) | Overwhelmed (less) | Tension (less) |
Fear (less) | Panic/panic attacks (less) | Worry (less) |
Fidgety (less) | Patient (more) | Â |
B Four-domain conceptual framework of life engagement | ||
|---|---|---|
Domain | Low | High |
Emotional (affect/mood) | Negative affect/mood, flat, depressed | Positive affect/mood, happy, hopeful |
Physical (energy) | Low energy, fatigued, tired | High energy, energized, motivated, productive |
Social (interest) | Low involvement, disengaged, anhedonia, disinterested | Involved, engaged, interested |
Cognitive (alertness/thinking) | Low arousal, brain fog, slowed thinking | High arousal, alert, clarity, attentive, aware |