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Table 5 Percentage of missing values in scores by mode of administration for patients with baseline data

From: Score equivalence of paper-, tablet-, and interactive voice response system-based versions of PROMIS, PRO-CTCAE, and numerical rating scales among cancer patients

Domain questionnaire and scale % Missing PSAQ % Missing CSAQ % Missing IVR p value all groups p value PSAQ vs CSAQ p value IVR vs others
Global/general health       
PROMIS global mental 2.8 0.7 2.3 .0201 .0050 .4151
PROMIS global physical 2.6 0.5 2.5 .0103 .0031 .0009
NRS overall QOL 1.4 0.5 2.5 .0166 .1119 .0198
NRS emotional well-being 1.4 0.3 2.5 .0068 .0482 .0119
NRS mental well-being 1.7 0.3 2.7 .0053 .0186 .0170
Physical function       
PROMIS physical function 1.2 1.2 3.7 .0021 .9290 .0009
NRS physical well-being 1.4 1.5 5.7 < .0001 .8513 < .0001
Social function       
PROMIS social function 1.7 1.0 5.2 < .0001 .2983 < .0001
NRS social activity 2.6 2.5 5.2 .0173 .9147 .0069
Emotional distress—anxiety       
PROMIS anxiety 2.0 1.0 5.2 < .0001 .1535 < .0001
NRS anxiety 2.0 1.5 5.4 .0001 .5133 < .0001
PRO-CTCAE anxiety frequency 2.0 1.5 5.4 .0001 .5133 < .0001
PRO-CTCAE anxiety severity 2.2 1.4 5.4 < .0001 .2782 < .0001
PRO-CTCAE anxiety interference 2.3 1.2 5.4 < .0001 .1298 < .0001
Emotional distress—depression       
PROMIS depression 2.5 1.4 4.8 .0012 .1517 .0008
NRS depression 2.8 1.9 4.8 .0109 .2812 .0068
CTC cheer frequency 2.6 1.9 4.8 .0088 .3611 .0047
CTC Cheer severity 3.3 2.0 6.2 .0006 .1822 .0004
CTC cheer interference 3.0 1.7 6.0 .0002 .1460 .0001
CTC sad frequency 3.0 1.7 6.0 .0002 .1460 .0001
CTC sad severity 2.5 1.5 6.0 < .0001 .2324 < .0001
CTC sad interference 2.5 1.7 6.0 < .0001 .3349 < .0001
Fatigue       
PROMIS fatigue 1.9 0.7 6.0 < .0001 .0660 < .0001
NRS fatigue 2.0 1.2 6.2 < .0001 .2476 < .0001
PRO-CTCAE fatigue severity 2.0 0.8 6.4 < .0001 .0866 < .0001
PRO-CTCAE fatigue interference 2.0 0.8 6.5 < .0001 .0866 < .0001
Sleep       
PROMIS sleep disturbance 0.8 0.5 6.2 < .0001 .5581 < .0001
NRS sleep overall 1.2 0.8 6.4 < .0001 .4976 < .0001
PRO-CTCAE sleep severity 1.4 0.7 5.9 < .0001 .2163 < .0001
PRO-CTCAE sleep interference 1.9 1.0 5.7 < .0001 .2155 < .0001
Pain       
PROMIS pain intensity 0.8 0.7 5.7 < .0001 .8393 < .0001
PROMIS pain interference 0.9 0.8 5.9 < .0001 .8753 < .0001
NRS pain frequency 1.1 0.8 5.9 < .0001 .6686 < .0001
NRS pain severity 0.9 1.2 5.9 < .0001 .6613 < .0001
PRO-CTCAE pain frequency 0.9 1.0 5.9 < .0001 .8786 < .0001
PRO-CTCAE pain severity 1.2 0.8 5.9 < .0001 .4976 < .0001
PRO-CTCAE pain interference 1.1 0.8 5.9 < .0001 .6686 < .0001
  1. The equality of proportion tests with χ2 test statistic were used to derive the p values. Because of multiple comparison concerns, p < .0001 will be used as a guideline to identify likely significant differences