Table 2 Symptoms and impacts of FCS reported by interview participants
From: Development of a novel PRO instrument for use in familial chylomicronemia syndrome
Concept | Interview number | Total, n (%) (N = 10) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ||
Symptoms | |||||||||||
Abdominal pain | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 10 (100.0) |
Loose bowel movements/diarrhea | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 8 (80.0) | ||
Difficulty thinking/mental fatigue/brain fog | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 (60.0) | ||||
Fatigue (physical) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 6 (60.0) | ||||
Blurred vision | ✓ | ✓ | ✓ | ✓ | ✓ | 5 (50.0) | |||||
Bloating | ✓ | ✓ | ✓ | ✓ | ✓ | 5 (50.0) | |||||
Difficulty remembering words or names | ✓ | ✓ | ✓ | ✓ | ✓ | 5 (50.0) | |||||
Xanthomas | ✓ | ✓ | ✓ | ✓ | 4 (40.0) | ||||||
Poor appetite | ✓ | ✓ | ✓ | ✓ | 4 (40.0) | ||||||
Nausea | ✓ | ✓ | ✓ | ✓ | 4 (40.0) | ||||||
Pain (not abdominal) | ✓ | ✓ | ✓ | ✓ | 4 (40.0) | ||||||
Difficulty concentrating | ✓ | ✓ | ✓ | 3 (30.0) | |||||||
Vomiting | ✓ | ✓ | ✓ | 3 (30.0) | |||||||
Weight loss | ✓ | ✓ | 2 (20.0) | ||||||||
Indigestion | ✓ | ✓ | 2 (20.0) | ||||||||
Muscle weakness | ✓ | ✓ | 2 (20.0) | ||||||||
Impacts | |||||||||||
Daily functioning | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 10 (100.0) |
Social functioning | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 10 (100.0) |
Mental/emotional well-being | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 10 (100.0) |
Ability to work/volunteer | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 9 (90.0) | |
Financial | ✓ | ✓ | ✓ | ✓ | ✓ | 5 (50.0) | |||||