Table 3 Number of patients and proxies reporting meaningful improvement or worsening from baseline to follow-up, percent exact agreement, and kappa statistic
Domain | Improvement | Worsening | ||||
|---|---|---|---|---|---|---|
Dyads indicating meaningful improvement, n (%) | % Exact Agreement | Kappa (95% CI) | Dyads indicating meaningful worsening, n (%) | % Exact Agreement | Kappa (95% CI) | |
Cognitive Function | 3 (7.5%) | 70.0% | 0.17 (− 0.14, 0.48) | 3 (7.5%) | 72.5% | 0.20 (− 0.13, 0.52) |
Physical Function | 6 (14.6%) | 73.2% | 0.34 (0.03, 0.65) | 0 (0.0%) | 75.6% | −0.05 (− 0.13, 0.04) |
Global Mental Health | 2 (4.9%) | 75.6% | 0.17 (−0.15, 0.49) | 4 (9.8%) | 65.9% | 0.17 (−0.11, 0.46) |
Global Physical Health | 5 (12.2%) | 68.3% | 0.22 (−0.11, 0.54) | 2 (4.9%) | 78.0% | 0.20 (−0.14, 0.54) |
Social Role Satisfaction | 4 (9.8%) | 58.5% | 0.04 (−0.26, 0.34) | 0 (0.0%) | 80.5% | −0.05 (− 0.12, 0.03) |
Anxiety | 11 (26.8%) | 63.4% | 0.27 (−0.03, 0.56) | 4 (9.8%) | 80.5% | 0.38 (0.03, 0.73) |
Depression | 4 (10.0%) | 60.0% | 0.05 (−0.26, 0.36) | 1 (2.5%) | 65.0% | −0.09 (− 0.36, 0.18) |
Fatigue | 8 (19.5%) | 61.0% | 0.19 (−0.11, 0.49) | 0 (0.0%) | 70.7% | −0.09 (− 0.20, 0.02) |
Pain Interference | 6 (14.6%) | 73.2% | 0.34 (0.03, 0.65) | 3 (7.3%) | 70.7% | 0.15 (−0.19, 0.48) |
Sleep Disturbance | 10 (25.0%) | 75.0% | 0.47 (0.19, 0.75) | 2 (5.0%) | 62.5% | 0.01 (−0.27, 0.28) |