Table 2 Clinical Characteristics of Children with CD
N | 2–4 years | 5–7 years | 8–11 years | 12–17 years | Total Child Sample |
|---|---|---|---|---|---|
3 | 6 | 9 | 20 | 38 | |
Time since diagnosis (months) | |||||
Mean (SD) | 9.3 (1.53) | 11.0 (13.73) | 12.9 (9.71) | 48.0 (44.17) | 30.8 (37.24) |
Median | 9.0 | 6.0 | 11.0 | 47.0 | 13.0 |
Min - Max | 8–11 | 2–38 | 2–30 | 2–168 | 2–168 |
Missing n | 0 | 0 | 0 | 0 | 0 |
CGI- CD severity (Last 30 days) – Clinician-reported | |||||
Remission | 0 (0.00) | 0 (0.00) | 1 (11.11) | 3 (15.00) | 4 (10.53) |
Mild | 3 (100.00) | 4 (66.67) | 4 (44.44) | 5 (25.00) | 16 (42.11) |
Moderate | 0 (0.00) | 1 (16.67) | 3 (33.33) | 12 (60.00) | 16 (42.11) |
Severe | 0 (0.00) | 0 (0.00) | 1 (11.11) | 0 (0.00) | 1 (2.63) |
Very Severe | 0 (0.00) | 1 (16.67) | 0 (0.00) | 0 (0.00) | 1 (2.63) |
Hospitalizations in past 12 months | |||||
1 | 0 | 1 | 1 | 3 | 5 |
2 | 0 | 1 | 0 | 0 | 1 |
0 | 3 | 4 | 8 | 17 | 32 |
Hemoglobin levels | |||||
Mean (SD) | 13.9 (0.35) | 11.8 (1.03) | 12.6 (1.52) | 13.0 (0.99) | 12.8 (1.19) |
Median | 13.9 | 11.4 | 13.0 | 13.1 | 13.0 |
Min - Max | 14–14 | 11–13 | 10–14 | 11–15 | 10–15 |
Missing n | 1 | 1 | 0 | 1 | 3 |
Surgery for CD? | |||||
Yes | 0 (0.00) | 1 (16.67) | 1 (11.11) | 7 (35.00)e | 9 (23.68) |
No | 3 (100.00) | 5 (83.33) | 8 (88.89) | 13 (65.00) | 29 (76.32) |
Surgery/Procedure typee | |||||
Fecal Resection | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (5.00) | 1 (2.63) |
Endoscopy | 0 (0.00) | 1 (16.67) | 1 (11.11) | 5 (25.00) | 7 (18.42) |
Comorbidities | |||||
Anemia | 0 (0.00) | 3 (50.00) | 4 (44.44) | 6 (30.00) | 13 (34.21) |
Nutritional disorders | 0 (0.00) | 1 (16.67) | 1 (11.11) | 2 (10.00) | 4 (10.53) |
Psychiatric disorder | 0 (0.00) | 1 (16.67) | 2 (22.22) | 1 (5.00) | 4 (10.53) |
Anal fissure/abscesses | 0 (0.00) | 1 (16.67) | 0 (0.00) | 3 (15.00) | 4 (10.53) |
Cardiac disease | 0 (0.00) | 0 (0.00) | 1 (11.11) | 0 (0.00) | 1 (2.63) |
Other | 0 (0.00) | 2 (33.33) | 3 (33.33) | 4 (20.00) | 9 (23.68) |
Child Treatments | |||||
Current Treatment | |||||
Biologics / Anti-TNF | 0 | 5 | 6 | 11 | 22 |
Vitamins and Probiotics | 3 | 3 | 2 | 6 | 14 |
Diet | 3 | 1 | 2 | 6 | 12 |
Aminosalicylate | 1 | 0 | 3 | 7 | 11 |
Immunomodulator | 0 | 0 | 3 | 6 | 9 |
Proton-pump inhibitor | 0 | 1 | 3 | 3 | 7 |
Corticosteroid Glucocorticoids | 0 | 1 | 1 | 3 | 5 |
OTC Pain Killer | 0 | 2 | 1 | 2 | 5 |
Stool softener or Laxative | 0 | 2 | 1 | 0 | 3 |
Gastrointestinal Agent | 0 | 0 | 0 | 3 | 3 |
Antibiotics | 1 | 1 | 0 | 0 | 2 |
Antiemetic | 0 | 0 | 1 | 1 | 2 |
Cognitive Behavioral Therapy | 0 | 0 | 1 | 0 | 1 |
Other | 0 | 0 | 0 | 1 | 1 |
Enteral Nutritional Therapy | 0 | 0 | 0 | 0 | 0 |
Previous Treatment | |||||
Biologics / Anti-TNF | 0 | 0 | 1 | 2 | 3 |
Vitamins and Probiotics | 0 | 0 | 1 | 1 | 2 |
Diet | 0 | 0 | 1 | 2 | 3 |
Aminosalicylate | 0 | 2 | 1 | 6 | 9 |
Immunomodulator | 0 | 1 | 1 | 2 | 4 |
Proton-pump inhibitor | 0 | 0 | 1 | 0 | 1 |
Corticosteroid Glucocorticoids | 0 | 2 | 4 | 9 | 15 |
OTC Pain Killer | 0 | 1 | 0 | 0 | 1 |
Stool softener or Laxative | 0 | 1 | 2 | 0 | 3 |
Gastrointestinal Agent | 0 | 0 | 0 | 0 | 0 |
Antibiotics | 0 | 0 | 1 | 0 | 1 |
Antiemetic | 0 | 1 | 1 | 0 | 2 |
Cognitive Behavioral Therapy | 0 | 0 | 0 | 0 | 0 |
Other | 0 | 0 | 0 | 0 | 0 |
Enteral Nutritional Therapy | 0 | 1 | 0 | 0 | 1 |