Table 8 Observational study construct validity hypotheses for HPES-Impact at baseline
From: Psychometric validation of the Hypoparathyroidism Patient Experience Scales (HPES)
HPES-Impact measure | Supporting measure | Construct validity hypothesis | Correlations |
|---|---|---|---|
Total | ▪ SII | Moderate to strong correlation with interference with QOL due to HP symptoms (SII) | SII Overall = 0.76 |
Physical functioning | ▪ SF-36 PCS ▪ SF-36 MCS | Moderate to strong correlations with SF-36 PCS scores (to support convergent validity) and less strong correlations with SF-36 MCS scores (to support divergent validity) | PCS = − 0.75 MCS = − 0.34 |
▪ HP-interference | Moderate to strong correlations with HP-Interference physical functioning scores | Physical functioning = 0.71 | |
Daily life | ▪ HP-interference | Moderate to strong correlations with SDS scores | SDS = 0.77 |
Moderate to strong correlations with HP-Interference daily life scores | Daily functioning = 0.77 | ||
Psychological well-being | ▪ HADS | Moderate to strong correlations with HADS anxiety and depression scores | Depression = 0.46 Anxiety = 0.54 |
▪ SF-36 PCS ▪ SF-36 MCS | Moderate to strong correlations with SF-36 MCS scores (to support convergent validity) and less strong correlations with SF-36 PCS scores (to support divergent validity) | PCS = −0.46 MCS = − 0.62 | |
▪ HP-interference | Moderate to strong correlations with HP-Interference emotional scores | Emotional Well-Being = 0.66 | |
Social life and relationships | ▪ MOS-SSS | Moderate to strong correlations with MOS-SSS domain scores | Emotional/informational = −0.22 Tangible = − 0.26 Affectionate = − 0.12 Positive social interaction = −0.21 Total = − 0.24 |
▪ Friends and family support | Moderate to strong correlations between with the family support item scores | −0.23 | |
▪ HP-interference | Moderate to strong correlations with HP-Interference social functioning scores | Social functioning = 0.76 |