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Table 5 Interpretation of change – HPES-Symptom

From: Psychometric validation of the Hypoparathyroidism Patient Experience Scales (HPES)

HPES-Symptom

Meaningful within-patient change

Total

Physical

Cognitive

Proposed threshold range

15–17

17–19

15–17

Anchor-based

 Primary anchor estimate mean (median)

17 (15)

19 (17)

13 (10)

 Supportive anchor estimate minimum (median)

16 (16)

14 (14)

17 (15)

 Supportive anchor estimate maximum (median)

19 (20)

17 (17)

21 (25)

Distribution-based

 Half-SD

11

11

15

 SEM

10

10

16

  1. HPES Hypoparathyroidism Patient Experience Scale, SD standard deviation, SEM standard error measurement