n = 42, Longitudinal follow-up
|
Baseline
|
4 months later
|
P value
|
---|
Mean (SD)/ Median (IQR)
|
---|
Thyroid function and immunological markers
|
Thyroxine Free
|
pmol/L
|
45.8 ± 22.2
|
15.6 ± 11.3
|
< 0.0001
|
TSH
|
mIU/L
|
0.03 (0.02–0.04)
|
1.42 (0.32–2.54)
|
0.0147
|
Thionamides
|
Carbimazole, mg/day
|
Dose
|
15.9 ± 8.5
|
11.2 ± 7.4
|
0.0006
|
Propylthiouracil, mg/day
|
Dose
|
90.0 ± 41.8
|
90.0 ± 54.8
|
1.000
|
Sonographic Volume
|
Thyroid volume
|
Cc
|
20.1 ± 12.3
|
15.5 ± 9.7
|
0.023
|
- SD Standard deviation, IQR Interquartile range, pmol/L picomoles per litre, mIU/L milli international units per litre, mg/day milligram per day, Cc Cubic centimetre