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Table 2 Biochemical and ultrasound thyroid volume at first visit and at 4 months later

From: Psychometric properties of the thyroid-specific quality of life questionnaire ThyPRO in Singaporean patients with Graves’ disease

n = 42, Longitudinal follow-up

Baseline

4 months later

P value

Mean (SD)/ Median (IQR)

Thyroid function and immunological markers

Thyroxine Free

pmol/L

45.8 ± 22.2

15.6 ± 11.3

< 0.0001

TSH

mIU/L

0.03 (0.02–0.04)

1.42 (0.32–2.54)

0.0147

Thionamides

Carbimazole, mg/day

Dose

15.9 ± 8.5

11.2 ± 7.4

0.0006

Propylthiouracil, mg/day

Dose

90.0 ± 41.8

90.0 ± 54.8

1.000

Sonographic Volume

Thyroid volume

Cc

20.1 ± 12.3

15.5 ± 9.7

0.023

  1. SD Standard deviation, IQR Interquartile range, pmol/L picomoles per litre, mIU/L milli international units per litre, mg/day milligram per day, Cc Cubic centimetre